| Austria Bundesliga | 09/07 10:00 | 1 | Maximilian Neuchrist v Florian Mayer | 6-7,6-3,3-6 | |
| US Open | 08/27 19:10 | 23 | [20] Borna Coric v Florian Mayer [193] | 6-2,6-2,5-7,6-4 | |
| Challenger Pullach | 08/06 15:45 | 25 | Alen Avidzba v Florian Mayer | 6-3,3-6,6-3 | |
| Challenger Pullach | 08/06 15:45 | 25 | Attila Balazs v Florian Mayer | Cancelled | |
| ATP Hamburg | 07/23 16:05 | 25 | [13] Pablo Carreno-Busta v Florian Mayer [94] | 2-6,6-1,7-6 | |
| Challenger Braunschweig | 07/09 14:55 | 25 | [91] Florian Mayer v Arthur De Greef [254] | 6-7,6-2,2-6 | |
| Wimbledon | 07/03 10:30 | 23 | [93] Jiri Vesely v Florian Mayer [91] | 7-6,6-4,4-6,6-1 | |
| ATP Antalya | 06/24 13:25 | 25 | [82] Florian Mayer v Joao Sousa [47] | 2-6,2-6 | |
| ATP Halle | 06/21 15:55 | 26 | [82] Florian Mayer v Andreas Seppi [50] | 2-6,4-6 | |
| ATP Halle | 06/19 12:20 | 25 | [25] Richard Gasquet v Florian Mayer [82] | 2-6,2-6 | |
| ATP Stuttgart | 06/13 12:50 | 26 | [100] Denis Istomin v Florian Mayer [85] | 6-3,6-4 | |
| ATP Stuttgart | 06/11 11:15 | 25 | [85] Florian Mayer v Yannick Maden [135] | 6-4,6-1 | |
| French Open | 05/29 13:45 | 23 | [64] Mischa Zverev v Florian Mayer [90] | 6-2,6-1,7-6 | |
| ATP Geneva | 05/21 12:10 | 25 | [90] Florian Mayer v Bernabe Zapata Miralles [281] | 3-6,2-6 | |
| ATP Rome Qual | 05/12 15:50 | 45 | [95] Dusan Lajovic v Florian Mayer [75] | 7-5,3-6,6-2 | |
| ATP Madrid Qual | 05/06 14:00 | 46 | [72] Florian Mayer v Dusan Lajovic [92] | 3-6,3-6 | |
| ATP Madrid Qual | 05/05 17:35 | 45 | [72] Florian Mayer v Marcel Granollers [129] | 7-6,7-6 | |
| ATP Munich | 04/30 15:20 | 25 | [72] Florian Mayer v Martin Klizan [122] | 6-3,4-6,3-6 | |
| ATP Monte Carlo | 04/16 13:35 | 24 | [74] Florian Mayer v Gilles Muller [28] | 5-7,4-6 | |
| ATP Monte Carlo Qual | 04/15 12:05 | 46 | [74] Florian Mayer v Ilya Ivashka [123] | 5-7,0-6 | |
| ATP Monte Carlo Qual | 04/14 14:30 | 45 | [74] Florian Mayer v Tommy Robredo [173] | 6-2,7-5 | |
| ATP Dubai | 02/26 12:00 | 25 | Roberto Bautista-Agut v Florian Mayer | 6-3,6-4 | |
| ATP Buenos Aires | 02/12 17:00 | 25 | Federico Delbonis v Florian Mayer | 7-6,6-4 | |
| ATP Sofia | 02/06 10:00 | 25 | Florian Mayer v Mirza Basic | 4-6,1-6 | |
| ATP Sofia Qual | 02/05 10:00 | - | Florian Mayer v Ernests Gulbis | 4-6,1-6 | |
| ATP Sofia Qual | 02/04 10:00 | 26 | Florian Mayer v John-Patrick Smith | 7-6,7-6 | |
| Australian Open | 01/16 03:25 | 23 | Evgeny Donskoy v Florian Mayer | 6-4,6-4,6-4 | |
| Challenger Canberra | 01/11 05:20 | 27 | Victor Estrella Burgos v Florian Mayer | 7-6,0-6,6-3 | |
| Challenger Canberra | 01/10 00:50 | 26 | Benjamin Mitchell v Florian Mayer | 4-6,6-7 | |
| Challenger Canberra | 01/08 01:15 | 25 | Yosuke Watanuki v Florian Mayer | 7-5,1-6,4-6 |