| WTA Doha | 02/09 10:00 | 14 | Yue Yuan v Saisai Zheng | 6-2,6-1 | |
| WTA Hua Hin | 01/27 09:35 | 14 | Saisai Zheng v Anastasia Tikhonova | 3-6,5-7 | |
| Australian Open Women | 01/17 05:15 | 23 | Irina-Camelia Begu v Saisai Zheng | Cancelled | |
| Australian Open Women | 01/17 05:40 | 23 | Saisai Zheng v Martina Trevisan | Cancelled | |
| WTA Melbourne 1 | 01/05 00:00 | 25 | [79] Saisai Zheng v Qinwen Zheng [126] | Cancelled | |
| ITF W100 Dubai | 11/23 07:40 | 25 | [256] Isabella Shinikova v Saisai Zheng [80] | 6-2,7-6 | |
| WTA Linz | 11/09 13:15 | 26 | [51] Jasmine Paolini v Saisai Zheng [87] | 6-1,2-6,6-4 | |
| WTA Linz | 11/07 15:10 | 25 | [77] Clara Burel v Saisai Zheng [87] | 4-6,1-6 | |
| WTA Courmayeur | 10/28 10:00 | 26 | [77] Saisai Zheng v Donna Vekic [97] | 3-6,4-6 | |
| WTA Courmayeur | 10/26 09:30 | 25 | [47] Petra Martic v Saisai Zheng [77] | 3-6,4-6 | |
| WTA Tenerife | 10/22 16:00 | 27 | [63] Maria C O Serrano v Saisai Zheng [86] | 7-5,6-1 | |
| WTA Tenerife | 10/21 09:30 | 26 | [86] Saisai Zheng v Clara Tauson [48] | 7-6,2-6,6-4 | |
| WTA Tenerife | 10/19 13:15 | 25 | [86] Saisai Zheng v Rebeka Masarova [169] | 6-4,6-2 | |
| WTA Indian Wells | 10/07 23:50 | 23 | [89] Saisai Zheng v Magdalena Frech [106] | 1-6,4-6 | |
| WTA Indian Wells | 10/07 18:00 | 23 | Saisai Zheng v Catherine McNally | Cancelled | |
| ITF W60 Berkeley | 09/29 20:50 | 25 | Saisai Zheng v Maria Kozyreva | 6-4,5-7,1-6 | |
| WTA Columbus | 09/25 15:00 | 28 | [83] Saisai Zheng v Nuria Parrizas-Diaz [86] | 7-5,3-6,4-6 | |
| WTA Columbus | 09/24 15:00 | 27 | [98] Lauren Davis v Saisai Zheng [83] | 6-1,2-6,2-6 | |
| WTA Columbus | 09/23 15:00 | 26 | [277] Alexa Glatch v Saisai Zheng [83] | 6-4,4-6,3-6 | |
| WTA Columbus | 09/21 21:20 | 25 | [184] Asia Muhammad v Saisai Zheng [83] | 7-6,3-6,6-7 | |
| ITF W60 Caldas da Rainha | 09/19 14:05 | 29 | [94] Saisai Zheng v Harmony Tan [128] | 6-4,3-6,6-3 | |
| ITF W60 Caldas da Rainha | 09/18 15:00 | 28 | [94] Saisai Zheng v Maddison Inglis [139] | 6-2,6-3 | |
| ITF W60 Caldas da Rainha | 09/17 10:50 | 27 | [94] Saisai Zheng v Marie Benoit [267] | 6-3,6-1 | |
| ITF W60 Caldas da Rainha | 09/16 09:00 | 26 | [94] Saisai Zheng v Amandine Hesse [209] | 2-6,7-5,7-5 | |
| ITF W60 Caldas da Rainha | 09/15 08:30 | 25 | [94] Saisai Zheng v Kyoka Okamura [302] | 6-2,6-1 | |
| Olympics 2020 - Women | 07/25 03:50 | 24 | [52] Saisai Zheng v Naomi Osaka [2] | 1-6,4-6 | |
| French Open Women | 06/03 09:00 | 24 | [81] Marta Kostyuk v Saisai Zheng [57] | 6-3,6-4 | |
| French Open Women | 05/31 16:55 | 23 | [57] Saisai Zheng v Sara Sorribes Tormo [49] | 4-6,6-4,6-4 | |
| WTA Rome | 05/11 11:55 | 24 | [58] Saisai Zheng v Barbora Krejcikova [40] | 2-6,0-6 | |
| WTA Madrid | 05/02 14:05 | 25 | [57] Saisai Zheng v Simona Halep [3] | 0-6,4-6 |