Head to Head
| NFL Preseason | 2019/08/16 23:00 | BUF Bills v CAR Panthers | W | 27-14 |
| NFL Preseason | 2018/08/09 23:00 | CAR Panthers v BUF Bills | L | 28-23 |
| NFL | 2018/02/02 09:34 | BUF Bills v CAR Panthers | L | 19-25 |
| NFL | 2017/09/17 17:00 | BUF Bills v CAR Panthers | L | 3-9 |
Home History
| NFL | 2020/01/04 21:35 | BUF Bills v HOU Texans | L | 19-22 |
| NFL | 2019/12/29 18:00 | NY Jets v BUF Bills | L | 13-6 |
| NFL | 2019/12/21 21:30 | BUF Bills v NE Patriots | L | 17-24 |
| NFL | 2019/12/16 01:20 | BUF Bills v PIT Steelers | W | 17-10 |
| NFL | 2019/12/08 18:00 | BAL Ravens v BUF Bills | L | 24-17 |
| NFL | 2019/11/28 21:30 | BUF Bills v DAL Cowboys | W | 26-15 |
| NFL | 2019/11/24 18:00 | DEN Broncos v BUF Bills | W | 3-20 |
| NFL | 2019/11/17 18:00 | BUF Bills v MIA Dolphins | W | 37-20 |
Away History
| NFL | 2019/12/29 18:00 | NO Saints v CAR Panthers | L | 42-10 |
| NFL | 2019/12/22 18:00 | CAR Panthers v IND Colts | L | 6-38 |
| NFL | 2019/12/15 18:00 | SEA Seahawks v CAR Panthers | L | 30-24 |
| NFL | 2019/12/08 18:00 | CAR Panthers v ATL Falcons | L | 20-40 |
| NFL | 2019/12/01 18:00 | WAS Commanders v CAR Panthers | L | 29-21 |
| NFL | 2019/11/24 18:00 | CAR Panthers v NO Saints | L | 31-34 |
| NFL | 2019/11/17 18:00 | ATL Falcons v CAR Panthers | L | 29-3 |
| NFL | 2019/11/10 21:25 | CAR Panthers v GB Packers | L | 16-24 |