[7] Schalke II 1-5 Borussia Dortmund II [2] 2020-11-21 12:00
Stadium: Mondpalast-Arena Round: 16
Referee: Kevin Domnick Home Manager: Torsten Frohling Away Manager: Enrico Maassen
Head to Head
| Germany Regionalliga West | 2019/10/26 12:00 | Borussia Dortmund II v Schalke II | W | 1-5 |
| Germany Regionalliga West | 2017/05/20 12:00 | Schalke II v Borussia Dortmund II | L | 0-1 |
| Germany Regionalliga West | 2016/12/17 13:30 | Borussia Dortmund II v Schalke II | D | 0-0 |
| Germany Regionalliga West | 2016/03/16 13:30 | Borussia Dortmund II v Schalke II | D | 1-1 |
| Germany Regionalliga West | 2015/10/28 14:30 | Schalke II v Borussia Dortmund II | D | 0-0 |
Home History
| Germany Regionalliga West | 2020/11/07 13:00 | Schalke II v Bonner SC | W | 2-1 |
| Germany Regionalliga West | 2020/11/04 18:30 | SC Wiedenbruck v Schalke II | D | 2-2 |
| Germany Regionalliga West | 2020/10/31 14:30 | Schalke II v Rot-Weiss Essen | D | 1-1 |
| Germany Regionalliga West | 2020/10/24 12:00 | Sportfreunde Lotte v Schalke II | D | 0-0 |
| Germany Regionalliga West | 2020/10/21 17:30 | Schalke II v Cologne II | W | 3-0 |
| Germany Regionalliga West | 2020/10/18 13:30 | Alemannia Aachen v Schalke II | D | 0-0 |
| Germany Regionalliga West | 2020/10/10 13:30 | Schalke II v Wuppertaler | L | 1-2 |
| Germany Regionalliga West | 2020/10/06 17:30 | Schalke II v Borussia M'gladbach II | L | 0-1 |
Away History
| Germany Regionalliga West | 2020/11/17 17:00 | SV Lippstadt 08 v Borussia Dortmund II | W | 0-4 |
| Germany Regionalliga West | 2020/11/03 18:30 | Borussia Dortmund II v SC Preussen Munster | W | 2-0 |
| Germany Regionalliga West | 2020/10/31 13:00 | SC Fortuna Köln v Borussia Dortmund II | W | 1-2 |
| Germany Regionalliga West | 2020/10/17 12:00 | Borussia Dortmund II v Rot Weiss Ahlen | W | 6-0 |
| Germany Regionalliga West | 2020/10/10 12:00 | Borussia Dortmund II v FC Wegberg-Beeck | W | 3-2 |
| Germany Regionalliga West | 2020/09/27 12:00 | Borussia Dortmund II v Bonner SC | D | 1-1 |
| Germany Regionalliga West | 2020/09/23 17:30 | SC Wiedenbruck v Borussia Dortmund II | W | 1-4 |
| Germany Regionalliga West | 2020/09/20 12:00 | Borussia Dortmund II v Rot-Weiss Essen | D | 1-1 |