Head to Head
| MLB | 2021/04/15 00:10 | CLE Guardians v CHI White Sox | L | 0-8 |
| MLB | 2021/04/14 00:10 | CLE Guardians v CHI White Sox | W | 2-0 |
| MLB | 2021/04/13 00:10 | CLE Guardians v CHI White Sox | L | 3-4 |
| MLB Exhibition | 2021/03/20 20:05 | CLE Guardians v CHI White Sox | L | 2-6 |
| MLB Spring Training | 2021/03/06 20:05 | CHI White Sox v CLE Guardians | L | 7-0 |
| MLB | 2020/09/24 22:10 | CHI White Sox v CLE Guardians | W | 4-5 |
| MLB | 2020/09/23 22:10 | CHI White Sox v CLE Guardians | W | 2-3 |
| MLB | 2020/09/22 22:10 | CHI White Sox v CLE Guardians | W | 3-5 |
Home History
| MLB | 2021/04/15 00:10 | CLE Guardians v CHI White Sox | L | 0-8 |
| MLB | 2021/04/14 00:10 | CLE Guardians v CHI White Sox | W | 2-0 |
| MLB | 2021/04/13 00:10 | CLE Guardians v CHI White Sox | L | 3-4 |
| MLB | 2021/04/11 17:10 | DET Tigers v CLE Guardians | W | 2-5 |
| MLB | 2021/04/10 22:10 | DET Tigers v CLE Guardians | W | 3-11 |
| MLB | 2021/04/09 23:10 | DET Tigers v CLE Guardians | W | 1-4 |
| MLB | 2021/04/07 17:10 | KC Royals v CLE Guardians | W | 2-4 |
| MLB | 2021/04/05 20:10 | KC Royals v CLE Guardians | L | 3-0 |
Away History
| MLB | 2021/04/15 00:10 | CLE Guardians v CHI White Sox | W | 0-8 |
| MLB | 2021/04/14 00:10 | CLE Guardians v CHI White Sox | L | 2-0 |
| MLB | 2021/04/13 00:10 | CLE Guardians v CHI White Sox | W | 3-4 |
| MLB | 2021/04/11 18:10 | KC Royals v CHI White Sox | L | 4-3 |
| MLB | 2021/04/08 22:20 | KC Royals v CHI White Sox | W | 0-6 |
| MLB | 2021/04/07 20:10 | CHI White Sox v SEA Mariners | L | 4-8 |
| MLB | 2021/04/07 02:10 | CHI White Sox v SEA Mariners | W | 10-4 |
| MLB | 2021/04/06 02:10 | CHI White Sox v SEA Mariners | W | 6-0 |