[2] TOR Maple Leafs 3-6 OTT Senators [11] 2017-10-21 23:00
Stadium: Canadian Tire Centre Round: 1
Head to Head
| NHL Pre-Season | 2017/09/19 23:30 | OTT Senators v TOR Maple Leafs | L | 5-2 |
| NHL Pre-Season | 2017/09/18 23:30 | OTT Senators v TOR Maple Leafs | L | 6-2 |
| NHL | 2017/02/19 00:00 | OTT Senators v TOR Maple Leafs | L | 6-3 |
| NHL | 2017/01/22 00:00 | OTT Senators v TOR Maple Leafs | L | 3-2 |
| NHL | 2017/01/15 00:00 | TOR Maple Leafs v OTT Senators | W | 4-2 |
| NHL | 2016/10/12 14:55 | TOR Maple Leafs v OTT Senators | L | 4-5 |
| NHL Pre-Season | 2016/10/05 01:18 | TOR Maple Leafs v OTT Senators | D | 0-0 |
Home History
| NHL | 2017/10/18 23:30 | DET Red Wings v TOR Maple Leafs | W | 3-6 |
| NHL | 2017/10/18 10:51 | VGS Golden Knights v TOR Maple Leafs | D | 0-0 |
| NHL | 2017/10/17 23:00 | TOR Maple Leafs v WAS Capitals | W | 2-0 |
| NHL | 2017/10/14 23:00 | TOR Maple Leafs v MON Canadiens | W | 4-3 |
| NHL | 2017/10/11 23:30 | NJ Devils v TOR Maple Leafs | L | 6-3 |
| NHL | 2017/10/09 23:00 | CHI Blackhawks v TOR Maple Leafs | W | 3-4 |
| NHL | 2017/10/07 23:00 | TOR Maple Leafs v NY Rangers | W | 8-5 |
| NHL | 2017/10/04 23:00 | WIN Jets v TOR Maple Leafs | W | 2-7 |
Away History
| NHL | 2017/10/19 23:30 | NJ Devils v OTT Senators | L | 5-4 |
| NHL | 2017/10/17 23:30 | VAN Canucks v OTT Senators | L | 3-0 |
| NHL | 2017/10/15 02:00 | OTT Senators v EDM Oilers | W | 6-1 |
| NHL | 2017/10/14 01:00 | OTT Senators v CAL Flames | W | 6-0 |
| NHL | 2017/10/11 02:00 | OTT Senators v VAN Canucks | W | 3-2 |
| NHL | 2017/10/07 23:00 | OTT Senators v DET Red Wings | L | 1-2 |
| NHL | 2017/10/05 23:30 | WAS Capitals v OTT Senators | L | 5-4 |
| NHL Pre-Season | 2017/09/30 23:00 | OTT Senators v MON Canadiens | L | 2-9 |