Stadium: Court 1 Round: 26 Ground: Grass
| French Open Women WD | 2021/06/04 09:00 | Muhammad/Pegula v Hradecka/Siegemund | 6-4,4-6,0-6 |
| French Open Women WD | 2021/06/02 10:15 | Paolini/Stojanovic v Muhammad/Pegula | 2-6,6-2,3-6 |
| WTA Miami WD | 2021/03/30 17:00 | Carter/Stefani v Muhammad/Pegula | 6-4,6-1 |
| WTA Miami WD | 2021/03/28 19:30 | Martic/Rogers v Muhammad/Pegula | 6-4,3-6,3-10 |
| WTA Miami WD | 2021/03/27 15:00 | Muhammad/Pegula v Melichar/Schuurs | 6-2,6-2 |
| Australian Open Women WD | 2021/02/10 00:00 | Aoyama/Shibahara v Muhammad/Pegula | 4-6,7-5,6-3 |
| WTA Yarra Valley Classic WD | 2021/02/02 07:45 | Kostyuk/Sasnovich v Muhammad/Pegula | 6-2,3-6,10-8 |
| French Open Women WD | 2020/10/07 12:00 | Muhammad/Pegula v Melichar/Swiatek | 3-6,4-6 |