[10] Portsmouth 2-1 AFC Wimbledon [18] 2021-11-20 15:00
Stadium: Fratton Park Round: 18
Referee: Thomas Bramall Home Manager: Danny Cowley Away Manager: Mark Robinson
Head to Head
| England EFL Trophy | 2021/09/07 18:45 | AFC Wimbledon v Portsmouth | L | 5-3 |
| England League 1 | 2021/05/01 14:00 | AFC Wimbledon v Portsmouth | W | 1-3 |
| England League 1 | 2021/01/19 19:00 | Portsmouth v AFC Wimbledon | W | 4-0 |
| England League 1 | 2020/01/11 15:00 | Portsmouth v AFC Wimbledon | W | 2-1 |
| England League 1 | 2019/10/19 14:00 | AFC Wimbledon v Portsmouth | L | 1-0 |
| England League 1 | 2019/01/01 15:00 | Portsmouth v AFC Wimbledon | W | 2-1 |
| England League 1 | 2018/10/13 14:00 | AFC Wimbledon v Portsmouth | W | 1-2 |
| England EFL Cup | 2018/08/14 18:45 | Portsmouth v AFC Wimbledon | L | 1-2 |
Home History
| England League 1 | 2021/11/13 15:00 | Wycombe v Portsmouth | W | 0-1 |
| England EFL Trophy | 2021/11/09 19:45 | Portsmouth v Crystal Palace U21 | W | 3-0 |
| England FA Cup | 2021/11/06 15:00 | Portsmouth v Harrow Borough | W | 1-0 |
| England League 1 | 2021/11/02 19:45 | Portsmouth v Cheltenham | D | 1-1 |
| England League 1 | 2021/10/30 14:00 | Portsmouth v Bolton | W | 1-0 |
| England League 1 | 2021/10/23 14:00 | Accrington Stanley v Portsmouth | D | 2-2 |
| England League 1 | 2021/10/19 18:45 | Portsmouth v Ipswich | L | 0-4 |
| England League 1 | 2021/10/16 14:00 | Rotherham v Portsmouth | L | 4-1 |
Away History
| England EFL Trophy | 2021/11/09 19:45 | Sutton Utd v AFC Wimbledon | L | 1-0 |
| England FA Cup | 2021/11/06 15:00 | AFC Wimbledon v Guiseley | W | 1-0 |
| England League 1 | 2021/10/30 14:00 | Cambridge Utd v AFC Wimbledon | L | 1-0 |
| England EFL Trophy | 2021/10/26 18:45 | AFC Wimbledon v Crystal Palace U21 | L | 0-2 |
| England League 1 | 2021/10/23 14:00 | AFC Wimbledon v Wigan | L | 0-2 |
| England League 1 | 2021/10/19 18:45 | Lincoln City v AFC Wimbledon | W | 0-1 |
| England League 1 | 2021/10/16 14:00 | AFC Wimbledon v Sheff Wed | D | 2-2 |
| England League 1 | 2021/10/02 14:00 | AFC Wimbledon v Burton Albion | D | 1-1 |