[1] Mamelodi Sundowns 4-1 Orlando Pirates [3] 2021-12-17 17:30
Stadium: Loftus Versfeld Stadium Round: 1
Referee: Home Manager: Steve Komphela Away Manager: Mandla Ncikazi
Head to Head
| South Africa Premier | 2021/09/25 13:00 | Orlando Pirates v Mamelodi Sundowns | W | 0-2 |
| South Africa Premier | 2021/05/02 13:00 | Orlando Pirates v Mamelodi Sundowns | W | 0-3 |
| South Africa Cup | 2021/04/15 16:00 | Mamelodi Sundowns v Orlando Pirates | W | 4-1 |
| South Africa Premier | 2021/01/02 13:30 | Mamelodi Sundowns v Orlando Pirates | W | 1-0 |
| South Africa Premier | 2020/08/11 16:00 | Mamelodi Sundowns v Orlando Pirates | D | 0-0 |
| South Africa Premier | 2020/01/15 17:30 | Orlando Pirates v Mamelodi Sundowns | L | 1-0 |
| South Africa Premier | 2019/04/01 17:30 | Orlando Pirates v Mamelodi Sundowns | D | 0-0 |
| South Africa Premier | 2018/11/10 13:30 | Mamelodi Sundowns v Orlando Pirates | D | 0-0 |
Home History
| South Africa Premier | 2021/12/14 15:30 | Mamelodi Sundowns v Baroka FC | W | 2-1 |
| South Africa Premier | 2021/12/11 18:15 | Supersport United v Mamelodi Sundowns | W | 0-1 |
| South Africa Premier | 2021/12/08 13:30 | Mamelodi Sundowns v Royal AM FC | W | 3-2 |
| South Africa Premier | 2021/12/04 18:15 | Stellenbosch FC v Mamelodi Sundowns | D | 1-1 |
| South Africa Premier | 2021/11/27 13:30 | Mamelodi Sundowns v Sekhukhune United FC | W | 2-0 |
| South Africa Premier | 2021/11/24 15:30 | Mamelodi Sundowns v Supersport United | D | 2-2 |
| South Africa Premier | 2021/11/20 15:30 | Cape Town City v Mamelodi Sundowns | D | 0-0 |
| South Africa Premier | 2021/11/07 15:30 | Marumo Gallants v Mamelodi Sundowns | W | 0-4 |
Away History
| South Africa Premier | 2021/12/14 17:30 | Moroka Swallows v Orlando Pirates | D | 1-1 |
| South Africa Premier | 2021/12/11 15:30 | Orlando Pirates v TS Galaxy | W | 2-0 |
| South Africa Premier | 2021/12/08 15:30 | Amazulu v Orlando Pirates | D | 1-1 |
| South Africa Premier | 2021/12/02 18:00 | Orlando Pirates v Baroka FC | D | 0-0 |
| CAF Confederations Cup | 2021/11/28 16:00 | LPRC Oilers FC v Orlando Pirates | W | 0-2 |
| South Africa Premier | 2021/11/24 15:30 | Stellenbosch FC v Orlando Pirates | W | 0-3 |
| South Africa Premier | 2021/11/20 13:30 | Golden Arrows v Orlando Pirates | D | 0-0 |
| South Africa Premier | 2021/11/06 13:30 | Kaizer Chiefs v Orlando Pirates | L | 2-1 |