[7] Exeter 1-0 Leyton Orient [15] 2022-02-08 19:45
Stadium: St James Park Round: 31
Referee: Carl Brook Home Manager: Matthew Taylor Away Manager: Kenneth Francis Jackett
Head to Head
| England League 2 | 2021/08/14 14:00 | Leyton Orient v Exeter | L | 3-0 |
| England League 2 | 2021/03/06 13:00 | Exeter v Leyton Orient | W | 4-0 |
| England League 2 | 2020/10/27 19:00 | Leyton Orient v Exeter | D | 1-1 |
| England League 2 | 2019/09/14 14:00 | Exeter v Leyton Orient | D | 2-2 |
| England League 2 | 2017/01/02 15:00 | Exeter v Leyton Orient | W | 4-0 |
| England League 2 | 2016/11/22 19:45 | Leyton Orient v Exeter | W | 0-1 |
| England League 2 | 2016/01/16 15:00 | Leyton Orient v Exeter | W | 1-3 |
| England League 2 | 2015/09/05 14:00 | Exeter v Leyton Orient | W | 4-0 |
Home History
| England League 2 | 2022/02/05 15:00 | Swindon v Exeter | W | 1-2 |
| England League 2 | 2022/01/29 15:00 | Exeter v Hartlepool | D | 0-0 |
| England League 2 | 2022/01/22 15:00 | Walsall v Exeter | W | 0-2 |
| England League 2 | 2022/01/15 15:00 | Exeter v Scunthorpe | W | 2-0 |
| England EFL Trophy | 2022/01/07 19:30 | Exeter v Portsmouth | L | 2-3 |
| England League 2 | 2022/01/04 19:45 | Forest Green v Exeter | D | 0-0 |
| England League 2 | 2022/01/01 15:00 | Sutton Utd v Exeter | L | 2-1 |
| England League 2 | 2021/12/11 15:00 | Exeter v Tranmere | L | 0-1 |
Away History
| England League 2 | 2022/02/05 15:00 | Leyton Orient v Colchester | L | 0-1 |
| England League 2 | 2022/02/01 19:45 | Bradford v Leyton Orient | D | 1-1 |
| England League 2 | 2022/01/29 15:00 | Mansfield v Leyton Orient | L | 2-0 |
| England League 2 | 2022/01/25 19:45 | Leyton Orient v Newport County | L | 0-1 |
| England League 2 | 2022/01/22 15:00 | Leyton Orient v Port Vale | D | 0-0 |
| England FA Cup | 2022/01/09 14:00 | Stoke v Leyton Orient | L | 2-0 |
| England League 2 | 2021/12/18 15:00 | Tranmere v Leyton Orient | L | 1-0 |
| England League 2 | 2021/12/11 15:00 | Leyton Orient v Crawley Town | L | 1-2 |