Stadium: Walter J. Zable Stadium at Cary Field Round: 1
Home Manager: Mike London Away Manager: Rob Ambrose
| NCAAF | 2019/11/16 18:00 | Towson v William & Mary | W | 31-10 |
| NCAAF | 2018/10/13 20:00 | William & Mary v Towson | W | 13-29 |
| NCAAF | 2017/11/11 19:00 | William & Mary v Towson | W | 14-26 |
| NCAAF | 2021/10/16 20:00 | Rhode Island v Towson | W | 7-28 |
| NCAAF | 2021/10/09 20:00 | Stony Brook v Towson | W | 14-21 |
| NCAAF | 2021/09/25 19:30 | Towson v San Diego State | L | 21-48 |
| NCAAF | 2021/09/18 22:00 | North Dakota State v Towson | L | 35-7 |
| NCAAF | 2021/09/11 22:00 | Towson v New Hampshire | L | 14-26 |
| NCAAF | 2021/09/04 20:00 | Towson v Morgan State | W | 31-0 |
| NCAAF | 2019/11/23 19:00 | Elon v Towson | L | 25-23 |
| NCAAF | 2019/11/16 18:00 | Towson v William & Mary | W | 31-10 |
| NCAAF | 2021/10/16 16:00 | William & Mary v Maine | L | 16-27 |
| NCAAF | 2021/10/09 19:30 | Albany v William & Mary | W | 24-31 |
| NCAAF | 2021/09/25 18:00 | William & Mary v Elon | W | 34-31 |
| NCAAF | 2021/09/18 17:00 | William & Mary v Colgate | W | 27-7 |
| NCAAF | 2021/09/11 22:00 | Lafayette v William & Mary | W | 3-24 |
| NCAAF | 2021/09/04 23:30 | William & Mary v Virginia | L | 0-43 |
| NCAAF | 2021/03/27 17:00 | James Madison v William & Mary | L | 38-10 |
| NCAAF | 2021/03/20 20:00 | Elon v William & Mary | W | 10-31 |