[12] Ayacucho FC 1-3 Cienciano [6] 2021-10-22 18:15
Stadium: Estadio Ciudad de Cumaná Round: 16
Referee: Victor Hugo Carrillo Casanova Home Manager: Walter Fiori Away Manager: Gerardo Pablo Ameli
Head to Head
| Peru Liga 1 | 2021/04/23 23:00 | Ayacucho FC v Cienciano | D | 1-1 |
| Peru Liga 1 | 2020/02/29 20:30 | Cienciano v Ayacucho FC | W | 1-4 |
| Peru Liga 1 | 2015/11/15 18:00 | Cienciano v Ayacucho FC | D | 1-1 |
| Peru Liga 1 | 2015/07/15 18:30 | Ayacucho FC v Cienciano | D | 0-0 |
| Peru Liga 1 | 2014/09/21 16:00 | Cienciano v Ayacucho FC | D | 0-0 |
| Peru Liga 1 | 2014/06/21 18:15 | Ayacucho FC v Cienciano | W | 3-1 |
Home History
| Peru Liga 1 | 2021/10/17 20:30 | Sporting Cristal v Ayacucho FC | L | 1-0 |
| Peru Liga 1 | 2021/10/01 15:30 | Ayacucho FC v Carlos Manucci | W | 3-2 |
| Peru Liga 1 | 2021/09/25 16:00 | UTC Cajamarca v Ayacucho FC | W | 0-2 |
| Peru Liga 1 | 2021/09/21 20:30 | Ayacucho FC v Alianza Atletico | L | 0-1 |
| Peru Liga 1 | 2021/09/17 23:00 | FBC Melgar v Ayacucho FC | D | 1-1 |
| Peru Liga 1 | 2021/09/11 18:15 | Ayacucho FC v Cusco FC | L | 1-3 |
| Peru Liga 1 | 2021/08/27 16:00 | Deportivo Binacional v Ayacucho FC | L | 3-1 |
| Peru Liga 1 | 2021/08/22 18:15 | Ayacucho FC v Cesar Vallejo | W | 2-1 |
Away History
| Peru Liga 1 | 2021/10/17 18:15 | Alianza Universidad v Cienciano | D | 1-1 |
| Peru Liga 1 | 2021/10/01 20:30 | Cienciano v Sporting Cristal | W | 2-1 |
| Peru Liga 1 | 2021/09/25 18:15 | Carlos Manucci v Cienciano | W | 1-3 |
| Peru Liga 1 | 2021/09/21 16:00 | Cienciano v UTC Cajamarca | D | 2-2 |
| Peru Liga 1 | 2021/09/17 16:00 | Alianza Atletico v Cienciano | D | 2-2 |
| Peru Liga 1 | 2021/09/12 23:00 | Cienciano v FBC Melgar | L | 0-1 |
| Peru Liga 1 | 2021/08/27 20:30 | Cusco FC v Cienciano | L | 3-0 |
| Peru Liga 1 | 2021/08/22 16:00 | Cienciano v Deportivo Binacional | W | 2-0 |