Stadium: Hinkle Fieldhouse
Home Manager: LaVall Jordan Away Manager: Marty Simmons
| NCAAB | 2021/12/08 01:00 | Eastern Illinois v Missouri | L | 44-72 |
| NCAAB | 2021/12/04 20:00 | Eastern Illinois v North Park | W | 76-71 |
| NCAAB | 2021/12/02 01:00 | Eastern Illinois v Northern Illinois | L | 45-55 |
| NCAAB | 2021/11/28 19:00 | Evansville v Eastern Illinois | L | 70-54 |
| NCAAB | 2021/11/24 17:00 | Albany NY v Eastern Illinois | L | 64-62 |
| NCAAB | 2021/11/23 00:00 | Eastern Illinois v Eastern Kentucky | L | 43-82 |
| NCAAB | 2021/11/19 01:00 | Eastern Illinois v Rockford | W | 96-64 |
| NCAAB | 2021/11/16 01:00 | Central Michigan v Eastern Illinois | L | 62-61 |
| NCAAB | 2021/12/08 02:00 | Butler v Oklahoma | W | 66-62 |
| NCAAB | 2021/11/30 22:00 | Saginaw Valley v Butler | W | 57-68 |
| NCAAB | 2021/11/25 02:00 | Butler v Chaminade | W | 84-51 |
| NCAAB | 2021/11/23 19:30 | Texas A&M v Butler | L | 57-50 |
| NCAAB | 2021/11/22 21:30 | Butler v Houston | L | 52-70 |
| NCAAB | 2021/11/18 00:00 | Michigan State v Butler | L | 73-52 |
| NCAAB | 2021/11/14 01:00 | Troy v Butler | W | 59-70 |
| NCAAB | 2021/11/12 23:30 | Central Arkansas v Butler | W | 53-85 |