Stadium: Fifth Third Arena
Home Manager: Wes Miller Away Manager: Quinton Ferrell
| NCAAB | 2021/11/16 00:00 | The Citadel v Presbyterian | W | 70-74 |
| NCAAB | 2021/11/13 00:00 | VMI v Presbyterian | W | 72-73 |
| NCAAB | 2021/11/10 00:00 | Presbyterian v Clemson | L | 53-64 |
| NCAAB | 2021/02/27 19:00 | Presbyterian v Hampton | L | 65-67 |
| NCAAB | 2021/02/22 23:00 | Charleston Southern v Presbyterian | L | 78-77 |
| NCAAB | 2021/02/18 22:00 | USC Upstate v Presbyterian | L | 65-51 |
| NCAAB | 2021/02/15 23:00 | USC Upstate v Presbyterian | W | 65-75 |
| NCAAB | 2021/02/12 21:00 | Presbyterian v Hampton | L | 57-62 |
| NCAAB | 2021/11/17 00:00 | Alabama A&M v Cincinnati | W | 66-89 |
| NCAAB | 2021/11/14 00:00 | Georgia Bulldogs v Cincinnati | W | 68-73 |
| NCAAB | 2021/11/10 00:00 | Evansville v Cincinnati | W | 43-65 |
| NCAAB | 2021/03/14 19:15 | Cincinnati v Houston | L | 54-91 |
| NCAAB | 2021/03/13 20:00 | Cincinnati v Wichita State | W | 60-59 |
| NCAAB | 2021/03/12 20:00 | Cincinnati v SMU | W | 74-71 |
| NCAAB | 2021/03/07 18:00 | Cincinnati v East Carolina | W | 82-69 |
| NCAAB | 2021/03/05 00:00 | Vanderbilt v Cincinnati | L | 78-64 |