[16] CD Real Santander Women 1-5 America de Cali Women [2] 2022-05-05 16:00
Stadium: Estadio Villa Concha Round: 16
Head to Head
| Colombia Liga Femenina | 2021/08/02 20:00 | America de Cali Women v CD Real Santander Women | L | 4-0 |
Home History
| Colombia Liga Femenina | 2022/05/01 20:00 | Deportes Tolima Women v CD Real Santander Women | L | 3-0 |
| Colombia Liga Femenina | 2022/04/17 18:00 | CD Real Santander Women v Internacional FC de Palmira Women | L | 1-4 |
| Colombia Liga Femenina | 2022/04/13 20:00 | Llaneros Women v CD Real Santander Women | L | 6-1 |
| Colombia Liga Femenina | 2022/04/10 16:00 | Atletico Bucaramanga Women v CD Real Santander Women | L | 2-0 |
| Colombia Liga Femenina | 2022/04/07 18:00 | CD Real Santander Women v Independiente Medellin Women | D | 0-0 |
| Colombia Liga Femenina | 2022/04/03 18:00 | Fortaleza FC Women v CD Real Santander Women | D | 1-1 |
| Colombia Liga Femenina | 2022/03/30 18:00 | CD Real Santander Women v Independiente Santa Fe Women | L | 0-2 |
| Colombia Liga Femenina | 2022/03/25 20:30 | Deportivo Cali Women v CD Real Santander Women | L | 7-0 |
Away History
| Colombia Liga Femenina | 2022/05/02 20:00 | America de Cali Women v Internacional FC de Palmira Women | W | 2-1 |
| Colombia Liga Femenina | 2022/04/24 20:00 | Llaneros Women v America de Cali Women | W | 0-3 |
| Colombia Liga Femenina | 2022/04/17 19:00 | America de Cali Women v Independiente Medellin Women | L | 1-2 |
| Colombia Liga Femenina | 2022/04/13 19:00 | Fortaleza FC Women v America de Cali Women | W | 0-3 |
| Colombia Liga Femenina | 2022/04/05 18:00 | America de Cali Women v Independiente Santa Fe Women | D | 2-2 |
| Colombia Liga Femenina | 2022/04/02 16:00 | Deportivo Cali Women v America de Cali Women | W | 0-4 |
| Colombia Liga Femenina | 2022/03/30 18:00 | America de Cali Women v Atletico Huila Women | W | 1-0 |
| Colombia Liga Femenina | 2022/03/26 22:00 | Deportivo Pereira Women v America de Cali Women | D | 1-1 |