[9] Santos Laguna 2-1 Leon [12] 2022-08-19 00:00
Stadium: Estadio TSM Corona Round: 9
Referee: Victor Alfonso Caceres Hernandez Home Manager: Eduardo Fentanes Away Manager: Renato Paiva
Head to Head
| Mexico Liga MX | 2022/04/25 00:00 | Santos Laguna v Leon | D | 1-1 |
| Mexico Liga MX | 2021/08/22 00:00 | Leon v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2021/03/22 01:06 | Santos Laguna v Leon | L | 1-2 |
| Mexico Liga MX | 2020/11/03 03:00 | Leon v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2020/01/20 00:45 | Santos Laguna v Leon | W | 3-2 |
| Mexico Liga MX | 2019/08/29 00:00 | Leon v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2019/03/03 01:00 | Leon v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2018/09/16 21:00 | Santos Laguna v Leon | W | 3-0 |
Home History
| Mexico Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2022/08/07 02:05 | Santos Laguna v Cruz Azul | W | 4-0 |
| Mexico Liga MX | 2022/08/01 00:05 | Santos Laguna v Atlas | W | 1-0 |
| Mexico Liga MX | 2022/07/23 22:00 | Toluca v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2022/07/17 00:05 | Santos Laguna v Chivas Guadalajara | D | 1-1 |
| Mexico Liga MX | 2022/07/09 02:05 | Puebla v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2022/07/04 00:05 | Santos Laguna v Monterrey | W | 4-3 |
| America Friendlies | 2022/06/19 01:11 | Monterrey v Santos Laguna | W | 0-1 |
Away History
| Mexico Liga MX | 2022/08/13 22:00 | Leon v Mazatlan FC | L | 0-3 |
| Mexico Liga MX | 2022/08/07 00:00 | Monterrey v Leon | L | 5-1 |
| Mexico Liga MX | 2022/08/01 02:05 | Leon v Club America | W | 3-2 |
| Mexico Liga MX | 2022/07/27 02:05 | Leon v Toluca | L | 0-1 |
| Mexico Liga MX | 2022/07/21 02:05 | Chivas Guadalajara v Leon | D | 0-0 |
| Mexico Liga MX | 2022/07/16 00:00 | Puebla v Leon | D | 1-1 |
| Mexico Liga MX | 2022/07/10 00:00 | Leon v Unam Pumas | D | 3-3 |
| Mexico Liga MX | 2022/07/03 22:00 | Atletico San Luis v Leon | W | 1-2 |