[11] Southampton 0-1 Man Utd [14] 2022-08-27 11:30
Stadium: St. Mary's Stadium Round: 4
Referee: Andrew Madley Home Manager: Ralph Hasenhuttl Away Manager: Erik ten Hag
Head to Head
| England Premier League | 2022/02/12 12:30 | Man Utd v Southampton | D | 1-1 |
| England Premier League | 2021/08/22 13:00 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2021/02/02 20:15 | Man Utd v Southampton | L | 9-0 |
| England Premier League | 2020/11/29 14:00 | Southampton v Man Utd | L | 2-3 |
| England Premier League | 2020/07/13 19:00 | Man Utd v Southampton | D | 2-2 |
| England Premier League | 2019/08/31 11:30 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2019/03/02 15:00 | Man Utd v Southampton | L | 3-2 |
| England Premier League | 2018/12/01 17:30 | Southampton v Man Utd | D | 2-2 |
Home History
| England EFL Cup | 2022/08/23 18:45 | Cambridge Utd v Southampton | W | 0-3 |
| England Premier League | 2022/08/20 14:00 | Leicester v Southampton | W | 1-2 |
| England Premier League | 2022/08/13 14:00 | Southampton v Leeds | D | 2-2 |
| England Premier League | 2022/08/06 14:00 | Tottenham v Southampton | L | 4-1 |
| Club Friendly List | 2022/07/30 14:00 | Southampton v Villarreal | L | 1-2 |
| Club Friendly List | 2022/07/27 18:45 | Southampton v Monaco | W | 3-1 |
| Club Friendly List | 2022/07/18 17:00 | Austria Klagenfurt v Southampton | D | 0-0 |
| Club Friendly List | 2022/07/16 12:00 | RB Leipzig v Southampton | L | 3-1 |
Away History
| England Premier League | 2022/08/22 19:00 | Man Utd v Liverpool | W | 2-1 |
| England Premier League | 2022/08/13 16:30 | Brentford v Man Utd | L | 4-0 |
| England Premier League | 2022/08/07 13:00 | Man Utd v Brighton | L | 1-2 |
| Club Friendly List | 2022/07/31 15:00 | Man Utd v Rayo Vallecano | D | 1-1 |
| Club Friendly List | 2022/07/30 11:45 | Man Utd v Atletico Madrid | L | 0-1 |
| Club Friendly List | 2022/07/23 09:45 | Man Utd v Aston Villa | D | 2-2 |
| Club Friendly List | 2022/07/19 10:10 | Man Utd v Crystal Palace | W | 3-1 |
| Club Friendly List | 2022/07/15 10:05 | Melbourne Victory v Man Utd | W | 1-4 |