[2] Leyton Orient 0-0 Northampton [3] 2022-10-15 14:00
Stadium: Matchroom Stadium Round: 14
Referee: Ollie Yates Home Manager: Richie Wellens Away Manager: Jon Brady
Head to Head
| England League 2 | 2022/04/23 14:00 | Leyton Orient v Northampton | L | 2-4 |
| England League 2 | 2021/11/27 15:00 | Northampton v Leyton Orient | L | 1-0 |
| Club Friendly List | 2020/08/22 12:00 | Northampton v Leyton Orient | L | 1-0 |
| England League 2 | 2020/01/21 19:45 | Leyton Orient v Northampton | D | 1-1 |
| England League 2 | 2019/10/05 14:00 | Northampton v Leyton Orient | W | 0-1 |
| England League 2 | 2016/02/13 15:00 | Leyton Orient v Northampton | L | 0-4 |
| England League 2 | 2015/09/26 14:00 | Northampton v Leyton Orient | D | 1-1 |
| England EFL Trophy | 2014/11/11 19:45 | Leyton Orient v Northampton | W | 2-0 |
Home History
| England League 2 | 2022/10/08 14:00 | Doncaster v Leyton Orient | D | 1-1 |
| England League 2 | 2022/10/01 14:00 | Leyton Orient v Newport County | L | 1-2 |
| England League 2 | 2022/09/24 14:00 | Barrow v Leyton Orient | W | 0-2 |
| England EFL Trophy | 2022/09/20 18:00 | Leyton Orient v Sutton Utd | W | 3-1 |
| England League 2 | 2022/09/17 14:00 | Leyton Orient v Walsall | W | 1-0 |
| England League 2 | 2022/09/13 18:45 | Rochdale v Leyton Orient | W | 0-1 |
| England League 2 | 2022/09/03 14:00 | Leyton Orient v Tranmere | W | 2-0 |
| England EFL Trophy | 2022/08/30 18:45 | Oxford Utd v Leyton Orient | L | 5-0 |
Away History
| England League 2 | 2022/10/08 14:00 | Northampton v Salford City | L | 0-1 |
| England League 2 | 2022/10/04 18:45 | Walsall v Northampton | L | 1-0 |
| England League 2 | 2022/10/01 14:00 | Swindon v Northampton | W | 1-2 |
| England League 2 | 2022/09/24 13:00 | Northampton v Stockport | W | 2-1 |
| England EFL Trophy | 2022/09/20 18:00 | Northampton v Cambridge Utd | L | 0-2 |
| England League 2 | 2022/09/17 14:00 | Northampton v Rochdale | W | 3-0 |
| England League 2 | 2022/09/13 18:45 | AFC Wimbledon v Northampton | W | 0-2 |
| England League 2 | 2022/09/03 14:00 | Northampton v Barrow | W | 3-1 |