Stadium: Tucker Stadium Round: 1
Home Manager: Dewayne Alexander Away Manager: Jed Stugart
| NCAAF | 2022/10/29 18:00 | Lindenwood v William Jewell College Cardinals | W | 64-23 |
| NCAAF | 2022/10/22 18:00 | Murray State v Lindenwood | W | 18-33 |
| NCAAF | 2022/10/15 19:00 | Lindenwood v Eastern Illinois | W | 37-34 |
| NCAAF | 2022/10/08 21:00 | Lindenwood v Central Arkansas | W | 52-49 |
| NCAAF | 2022/10/01 18:00 | SE Missouri St v Lindenwood | L | 49-28 |
| NCAAF | 2022/09/24 23:00 | Lindenwood v Tennessee Martin | L | 26-56 |
| NCAAF | 2022/09/17 23:00 | Lindenwood v Keiser University Seahawks | W | 37-3 |
| NCAAF | 2022/09/10 23:00 | Lindenwood v Houston Christian | W | 21-20 |
| NCAAF | 2022/10/29 19:00 | Tennessee Tech v Eastern Illinois | W | 20-17 |
| NCAAF | 2022/10/22 19:00 | Tennessee Tech v Kennesaw State | L | 30-33 |
| NCAAF | 2022/10/15 23:00 | Tennessee State v Tennessee Tech | L | 30-14 |
| NCAAF | 2022/10/08 19:00 | Tennessee Tech v SE Missouri St | L | 20-34 |
| NCAAF | 2022/10/01 19:00 | Tennessee Tech v Tennessee Martin | L | 28-45 |
| NCAAF | 2022/09/17 23:00 | Samford v Tennessee Tech | L | 33-28 |
| NCAAF | 2022/09/10 23:00 | Texas A&M-Commerce v Tennessee Tech | W | 25-26 |
| NCAAF | 2022/09/03 00:00 | Tennessee Tech v Kansas | L | 10-56 |