[11] James Madison 32-28 Appalachian State [2] 2022-09-24 19:30
Stadium: Kidd Brewer Stadium Round: 1
Home Manager: Shawn Clark Away Manager: Curt Cignetti
Home History
| NCAAF | 2022/09/10 20:00 | Norfolk State v James Madison | W | 7-63 |
| NCAAF | 2022/09/03 22:00 | Middle Tennessee St. v James Madison | W | 7-44 |
| NCAAF | 2021/12/18 02:15 | James Madison v North Dakota State | L | 14-20 |
| NCAAF | 2021/12/11 00:00 | Montana v James Madison | W | 6-28 |
| NCAAF | 2021/12/04 19:00 | SE Louisiana v James Madison | W | 20-59 |
| NCAAF | 2021/11/20 19:00 | Towson v James Madison | W | 10-56 |
| NCAAF | 2021/11/13 20:30 | James Madison v William & Mary | W | 32-22 |
| NCAAF | 2021/11/06 19:30 | Campbell v James Madison | W | 14-51 |
Away History
| NCAAF | 2022/09/17 19:30 | Troy v Appalachian St | W | 28-32 |
| NCAAF | 2022/09/10 19:30 | Appalachian St v Texas A&M | W | 17-14 |
| NCAAF | 2022/09/03 16:00 | North Carolina v Appalachian St | L | 63-61 |
| NCAAF Bowl Games | 2021/12/18 16:00 | Appalachian St v Western Kentucky | L | 38-59 |
| NCAAF | 2021/12/04 20:30 | Appalachian St v Lafayette | L | 16-24 |
| NCAAF | 2021/11/27 19:30 | Georgia Southern v Appalachian St | W | 3-27 |
| NCAAF | 2021/11/20 20:30 | Appalachian St v Troy | W | 45-7 |
| NCAAF | 2021/11/13 19:30 | South Alabama v Appalachian St | W | 7-31 |