Stadium: Tenney Stadium at Leonidoff Field Round: 1
Home Manager: Jim Parady Away Manager: Steve Englehart
| NCAAF | 2022/10/22 17:00 | St.Thomas MIN v Presbyterian | L | 46-17 |
| NCAAF | 2022/10/15 21:00 | Presbyterian v San Diego | L | 3-28 |
| NCAAF | 2022/10/08 16:00 | Valparaiso v Presbyterian | L | 41-21 |
| NCAAF | 2022/10/01 17:00 | Presbyterian v Morehead State | L | 10-14 |
| NCAAF | 2022/09/24 23:00 | Davidson Wildcats v Presbyterian | L | 56-24 |
| NCAAF | 2022/09/17 19:30 | Presbyterian v Western Carolina | L | 21-77 |
| NCAAF | 2022/09/10 17:00 | Presbyterian v Lynchburg Dragons | W | 21-13 |
| NCAAF | 2022/09/03 23:00 | Presbyterian v Austin Peay | L | 0-63 |
| NCAAF | 2022/10/22 17:00 | Marist v Butler | L | 10-31 |
| NCAAF | 2022/10/15 16:00 | Dayton v Marist | L | 24-7 |
| NCAAF | 2022/10/08 17:00 | Marist v Stetson Hatters | W | 45-31 |
| NCAAF | 2022/10/01 16:00 | St.Thomas MIN v Marist | L | 38-24 |
| NCAAF | 2022/09/24 18:00 | Marist v Drake Bulldogs | W | 30-25 |
| NCAAF | 2022/09/17 22:00 | Columbia v Marist | L | 38-3 |
| NCAAF | 2022/09/03 16:00 | Georgetown v Marist | L | 43-12 |
| NCAAF | 2021/11/20 17:00 | Butler v Marist | L | 28-21 |