Stadium: Orleans Arena
Home Manager: Steve Lavin Away Manager: Austin Claunch
| NCAAB | 2022/11/26 00:00 | UC Irvine v Nicholls State | L | 83-56 |
| NCAAB | 2022/11/23 01:00 | Nicholls State v Jarvis Christian | W | 97-52 |
| NCAAB | 2022/11/20 02:00 | Nicholls State v BYU | L | 73-87 |
| NCAAB | 2022/11/11 03:00 | Nicholls State v Wyoming | L | 68-79 |
| NCAAB | 2022/11/08 02:30 | Nicholls State v Arizona | L | 75-117 |
| NIT | 2022/03/17 00:00 | Nicholls State v SMU | L | 58-68 |
| NCAAB | 2022/03/11 23:00 | Texas A&M Corpus v Nicholls State | L | 71-64 |
| NCAAB | 2022/03/05 21:30 | New Orleans v Nicholls State | W | 85-92 |
| NCAAB | 2022/11/26 02:30 | San Diego v New Mexico State | L | 77-90 |
| NCAAB | 2022/11/22 03:00 | San Diego v San Diego Christian | W | 98-69 |
| NCAAB | 2022/11/18 03:00 | Utah State v San Diego | L | 91-89 |
| NCAAB | 2022/11/13 22:00 | NJIT v San Diego | W | 64-74 |
| NCAAB | 2022/11/10 03:00 | Florida Gulf Coast v San Diego | W | 73-79 |
| NCAAB | 2022/11/08 03:30 | San Diego v Sonoma State | W | 81-59 |
| NCAAB | 2022/03/05 04:00 | San Diego v Portland | L | 55-73 |
| NCAAB | 2022/03/04 04:00 | Pepperdine v San Diego | W | 67-74 |