[17] Chivas Guadalajara 1-2 Santos Laguna [7] 2018-08-12 23:00
Stadium: Estadio Akron Round: 4
Referee: Marco Antonio Ortiz Nava Home Manager: Jose Cardozo Away Manager: Robert Siboldi
Head to Head
| Mexico Liga MX | 2018/02/11 03:06 | Chivas Guadalajara v Santos Laguna | L | 0-2 |
| Mexico Cup | 2017/08/30 02:00 | Chivas Guadalajara v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2017/08/24 01:30 | Santos Laguna v Chivas Guadalajara | D | 1-1 |
| Mexico Cup | 2017/07/26 23:55 | Santos Laguna v Chivas Guadalajara | L | 2-0 |
| World Club Friendlies | 2017/07/02 22:00 | Chivas Guadalajara v Santos Laguna | L | 0-5 |
| Mexico Liga MX | 2017/02/05 22:00 | Chivas Guadalajara v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2016/08/14 23:00 | Santos Laguna v Chivas Guadalajara | W | 0-1 |
| Mexico Liga MX | 2016/05/07 02:30 | Santos Laguna v Chivas Guadalajara | W | 0-1 |
Home History
| Mexico Cup | 2018/08/09 02:00 | Oaxaca v Chivas Guadalajara | D | 0-0 |
| Mexico Liga MX | 2018/08/05 17:00 | Toluca v Chivas Guadalajara | D | 2-2 |
| Mexico Cup | 2018/08/01 02:00 | Chivas Guadalajara v Atletico Morelia | W | 3-2 |
| Mexico Liga MX | 2018/07/29 02:06 | Chivas Guadalajara v Cruz Azul | L | 0-1 |
| Mexico Liga MX | 2018/07/22 02:00 | Tijuana v Chivas Guadalajara | L | 2-1 |
| Europe Friendlies | 2018/07/13 00:00 | Atletico Nacional Medellin v Chivas Guadalajara | L | 7-6 |
| World Club Friendlies | 2018/07/06 01:00 | Chivas Guadalajara v Leon | D | 0-0 |
| Mexico Liga MX | 2018/04/29 02:06 | Chivas Guadalajara v Leon | L | 0-2 |
Away History
| Mexico Cup | 2018/08/08 00:00 | Santos Laguna v Club Celaya | D | 1-1 |
| Mexico Liga MX | 2018/08/05 23:00 | Santos Laguna v Puebla | W | 2-0 |
| Mexico Cup | 2018/08/01 02:00 | Pachuca v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2018/07/28 00:00 | Atletico Morelia v Santos Laguna | L | 3-1 |
| Mexico Liga MX | 2018/07/22 23:00 | Santos Laguna v Lobos BUAP | W | 2-1 |
| Mexico Champion of Champions | 2018/07/16 01:00 | Tigres UANL v Santos Laguna | L | 4-0 |
| Mexico Liga MX | 2018/05/21 00:00 | Toluca v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2018/05/18 01:00 | Santos Laguna v Toluca | W | 2-1 |