[18] Deportivo Pereira 2-0 Once Caldas [16] 2021-03-01 23:00
Stadium: Estadio Hernan Ramirez Villegas Round: 10
Referee: Andres Jose Rojas Noguera Home Manager: Alexis Marquez Away Manager: Eduardo Lara Lozano
Head to Head
| Colombia Primera A | 2020/03/02 01:15 | Deportivo Pereira v Once Caldas | L | 1-3 |
| World Club Friendlies | 2020/01/12 20:30 | Once Caldas v Deportivo Pereira | W | 0-1 |
| World Club Friendlies | 2018/07/14 01:00 | Deportivo Pereira v Once Caldas | W | 1-0 |
| World Club Friendlies | 2015/07/05 20:30 | Deportivo Pereira v Once Caldas | L | 0-3 |
| Colombia Cup | 2014/08/07 21:00 | Deportivo Pereira v Once Caldas | W | 2-1 |
| Colombia Cup | 2014/07/03 00:00 | Once Caldas v Deportivo Pereira | L | 5-2 |