[7] River Plate 3-2 Colon [1] 2021-04-12 00:00
Stadium: Estadio Monumental Antonio Vespucio Liberti Round: 9
Referee: Facundo Tello Figueroa Home Manager: Marcelo Gallardo Away Manager: Eduardo Dominguez
Head to Head
| Argentina Superliga | 2019/10/30 00:20 | River Plate v Colon | W | 2-1 |
| Argentina Superliga | 2018/10/20 00:15 | Colon v River Plate | L | 1-0 |
| Argentina Superliga | 2018/05/08 00:15 | Colon v River Plate | D | 0-0 |
| Argentina Superliga | 2017/06/25 23:00 | Colon v River Plate | D | 0-0 |
| Argentina Liga Profesional | 2016/03/13 23:00 | Colon v River Plate | L | 4-1 |
| Argentina Liga Profesional | 2015/07/25 20:15 | River Plate v Colon | W | 3-1 |
| Argentina Cup | 2014/08/20 23:30 | River Plate v Colon | W | 4-2 |