[3] Independiente Santa Fe 0-0 River Plate [2] 2021-05-07 00:00
Stadium: General Pablo Rojas Round: 3
Referee: Alexis Adrian Herrera Hernandez Home Manager: Harold Rivera Roa Away Manager: Marcelo Gallardo
Head to Head
| Copa Libertadores | 2018/05/04 00:30 | Independiente Santa Fe v River Plate | L | 0-1 |
| Copa Libertadores | 2018/04/05 22:15 | River Plate v Independiente Santa Fe | D | 0-0 |
| Recopa Sudamericana | 2016/08/26 00:15 | River Plate v Independiente Santa Fe | L | 2-1 |