| ITF W25 Cancun | 02/06 20:00 | 44 | Lauren Proctor v Maria Jose Portillo Ramirez | 3-6,1-6 | |
| ITF W60 Rome GA | 01/31 14:50 | 54 | [258] Marcela Zacarias v Maria Jose Portillo Ramirez [500] | 6-1,6-1 | |
| ITF W60 Orlando | 01/24 19:45 | 54 | Maria Jose Portillo Ramirez v Vera Lapko | Cancelled | |
| ITF W15 Cancun | 01/23 14:00 | 29 | Hina Inoue v Maria Jose Portillo Ramirez | 1-6,6-3,7-6 | |
| ITF W15 Cancun | 01/22 15:00 | 28 | Natalia Siedliska v Maria Jose Portillo Ramirez | 6-7,2-6 | |
| ITF W15 Cancun | 01/21 15:00 | 27 | Katarina Kuzmova v Maria Jose Portillo Ramirez | 0-6,3-6 | |
| ITF W15 Cancun | 01/20 18:15 | 26 | Lexington Reed v Maria Jose Portillo Ramirez | 3-6,2-6 | |
| ITF W15 Cancun | 01/19 20:05 | 25 | Esther Vyrlan v Maria Jose Portillo Ramirez | 3-6,3-6 | |
| ITF W25 Naples | 11/16 17:20 | 54 | Maria Jose Portillo Ramirez v Kennedy Shaffer | 2-6,7-6,10-12 | |
| ITF W25 Naples | 11/15 15:30 | 54 | Maria Jose Portillo Ramirez v Eleana Yu | 6-4,6-1 | |
| ITF W25 Daytona Beach | 11/13 15:00 | 28 | [235] Alycia Parks v Maria Jose P Ramirez [462] | 6-2,2-6,6-4 | |
| ITF W25 Daytona Beach | 11/12 14:55 | 27 | [269] Na-Lae Han v Maria Jose P Ramirez [462] | 2-6,4-6 | |
| ITF W25 Daytona Beach | 11/11 16:25 | 26 | [387] Alice Rame v Maria Jose P Ramirez [462] | 6-4,1-6,3-6 | |
| ITF W25 Daytona Beach | 11/10 15:55 | 25 | [462] Maria Jose P Ramirez v Ipek Oz [296] | 6-4,6-2 | |
| ITF W25 Daytona Beach | 11/09 16:10 | 54 | Maria Jose P Ramirez v Christina Rosca | 6-3,3-6,11-9 | |
| ITF W25 Daytona Beach | 11/08 16:00 | 54 | Maria Jose Portillo Ramirez v Lexington Reed | 6-1,6-3 | |
| ITF W25 Orlando | 11/06 15:30 | 27 | [479] Maria Jose Portillo Ramirez v Amina Anshba [302] | 1-6,6-7 | |
| ITF W25 Orlando | 11/04 15:00 | 26 | [308] Fernanda Contreras Gomez v Maria Jose Portillo Ramirez [479] | 7-5,6-7,1-6 | |
| ITF W25 Orlando | 11/03 19:05 | 25 | [479] Maria Jose Portillo Ramirez v Chieh-Yu Hsu [258] | 6-2,6-7,6-1 | |
| ITF W25 Orlando | 11/02 13:55 | 54 | Maria Jose Portillo Ramirez v Katja Wiersholm | 6-1,6-3 | |
| ITF W25 Orlando | 11/01 17:00 | 54 | Maria Jose Portillo Ramirez v Maria Kononova | 6-4,6-1 | |
| ITF W25 Austin | 10/26 17:40 | 54 | Maria Jose Portillo Ramirez v Liga Dekmeijere | 6-2,4-6,7-10 | |
| ITF W25 Austin | 10/25 17:00 | 54 | Maria Jose Portillo Ramirez v Rachel Gailis | 6-4,7-5 | |
| ITF W15 Cancun | 10/14 17:00 | 26 | Rachel Gailis v Maria Jose Portillo Ramirez | 7-5,6-7,7-6 | |
| ITF W15 Cancun | 10/13 17:00 | 25 | Maria I Yapur Lopez v Maria Jose Portillo Ramirez | 1-6,1-6 | |
| ITF W15 Cancun | 10/10 15:30 | 29 | Darja Semenistaja v Maria Jose Portillo Ramirez | 5-7,7-6,6-0 | |
| ITF W15 Cancun | 10/09 15:00 | 28 | Paris Corley v Maria Jose Portillo Ramirez | 2-6,2-6 | |
| ITF W15 Cancun | 10/08 15:00 | 27 | Yuliana Monroy v Maria Jose Portillo Ramirez | 5-7,2-6 | |
| ITF W15 Cancun | 10/07 17:45 | 26 | Anna Ulyashchenko v Maria Jose Portillo Ramirez | 6-7,4-6 | |
| ITF W15 Cancun | 10/06 21:05 | 25 | Jana Kolodynska v Maria Jose Portillo Ramirez | Retired |