| ITF W80 Macon | 10/22 14:00 | 25 | Monica Puig v Francesca Di Lorenzo | Cancelled | |
| ITF W80 Macon | 10/21 22:10 | 25 | [127] Astra Sharma v Francesca Di Lorenzo [141] | 3-6,4-6 | |
| French Open Women | 09/24 11:00 | 15 | [135] Francesca Di Lorenzo v Elena Gabriela Ruse [179] | 2-6,5-7 | |
| French Open Women | 09/22 12:35 | 14 | [135] Francesca Di Lorenzo v Marina Melnikova [192] | 6-4,6-0 | |
| ITF W80 Cagnes-Sur-Mer | 09/17 14:55 | 26 | [117] Oceane Dodin v Francesca Di Lorenzo [134] | 6-2,6-3 | |
| ITF W80 Cagnes-Sur-Mer | 09/15 07:50 | 25 | [152] Anhelina Kalinina v Francesca Di Lorenzo [134] | 2-6,3-6 | |
| US Open Women | 08/31 15:00 | 23 | [129] Francesca Di Lorenzo v Aliaksandra Sasnovich [106] | 6-2,6-7,0-6 | |
| WTA New York | 08/20 21:00 | 44 | [128] Francesca Di Lorenzo v Paula Badosa [94] | 4-6,3-6 | |
| WTA Lexington | 08/11 15:00 | 25 | Francesca Di Lorenzo v Catherine Bellis | 1-6,2-6 | |
| WTA Lexington | 08/10 14:00 | 168 | [128] Francesca Di Lorenzo v Olga Govortsova [135] | 1-6,2-6 | |
| WTA Lexington | 08/09 16:15 | 45 | [128] Francesca Di Lorenzo v Claire Liu [235] | 6-3,5-7,7-6 | |
| Matchplay 120 Women | 07/09 19:05 | 1 | [128] Francesca Di Lorenzo v Varvara Lepchenko [178] | 0-6,2-6 | |
| Matchplay 120 Women | 07/09 15:30 | - | [128] Francesca Di Lorenzo v Ann Li [131] | Cancelled | |
| Matchplay 120 Women | 07/03 15:00 | 1 | [128] Francesca Di Lorenzo v Grace Min [287] | 6-2,6-4 | |
| Matchplay 120 Women | 07/02 16:00 | 1 | [128] Francesca Di Lorenzo v Ann Li [131] | Interrupted | |
| Matchplay 120 Women | 06/18 15:00 | 1 | [128] Francesca Di Lorenzo v Grace Min [287] | 4-6,7-5,6-2 | |
| Matchplay 120 Women | 06/17 15:00 | - | [128] Francesca Di Lorenzo v Jamie Loeb [277] | 6-3,6-2 | |
| Matchplay 120 Women | 06/12 21:00 | - | Caroline Dolehide v Francesca Di Lorenzo | View | |
| US Pro Tennis Series Women | 05/14 19:35 | 1 | Francesca Di Lorenzo v Channelle Van Nguyen | 6-3,6-0 | |
| US Pro Tennis Series Women | 05/14 14:30 | 1 | [128] Francesca Di Lorenzo v Marine Partaud [488] | 6-4,6-0 | |
| US Pro Tennis Series Women | 05/12 20:30 | - | Anastasia E Nefedova v Francesca Di Lorenzo | View | |
| US Pro Tennis Series Women | 05/12 19:00 | 1 | Anastasia E Nefedova v Francesca Di Lorenzo | 4-6,2-6 | |
| US Pro Tennis Series Women | 05/12 16:00 | 1 | [391] Jennifer Elie v Francesca Di Lorenzo [128] | 3-6,4-6 | |
| US Pro Tennis Series Women | 05/04 22:00 | - | Francesca Di Lorenzo v Anastasia Sysoeva | 6-0,6-2 | |
| US Pro Tennis Series Women | 05/04 17:30 | - | [368] Alycia Parks v Francesca Di Lorenzo [128] | 6-4,2-6,0-1 | |
| WTA Indian Wells | 03/03 18:00 | 24 | [105] Katarina Zavatska v Francesca Di Lorenzo [124] | 1-6,6-1,6-3 | |
| WTA Acapulco | 02/25 22:00 | 25 | [394] Katie Boulter v Francesca Di Lorenzo [120] | 2-6,6-3,6-2 | |
| WTA Acapulco | 02/24 00:55 | 64 | [120] Francesca Di Lorenzo v Usue Maitane Arconada [132] | 3-6,3-6 | |
| WTA Acapulco | 02/23 02:35 | 45 | [120] Francesca Di Lorenzo v Maria Portillo Ramirez [421] | 6-3,6-1 | |
| ITF W100 Midland | 02/06 17:00 | 26 | [278] Catherine Harrison v Francesca Di Lorenzo [118] | 6-3,6-0 |