River Plate 2-1 Independiente Santa Fe 2021-05-20 00:00
Stadium: Estadio Monumental Antonio Vespucio Liberti Round: 5
Referee: Victor Hugo Carrillo Casanova Home Manager: Marcelo Gallardo Away Manager: Harold Rivera Roa
Head to Head
| Copa Libertadores | 2021/05/07 00:00 | Independiente Santa Fe v River Plate | D | 0-0 |
| Copa Libertadores | 2018/05/04 00:30 | Independiente Santa Fe v River Plate | W | 0-1 |
| Copa Libertadores | 2018/04/05 22:15 | River Plate v Independiente Santa Fe | D | 0-0 |
| Recopa Sudamericana | 2016/08/26 00:15 | River Plate v Independiente Santa Fe | W | 2-1 |
Home History
| Argentina Copa de la Liga Profesional | 2021/05/16 20:30 | Boca Juniors v River Plate | L | 5-3 |
| Copa Libertadores | 2021/05/13 00:00 | Junior v River Plate | D | 1-1 |
| Argentina Copa de la Liga Profesional | 2021/05/09 17:30 | River Plate v CA Aldosivi | W | 4-1 |
| Copa Libertadores | 2021/05/07 00:00 | Independiente Santa Fe v River Plate | D | 0-0 |
| Argentina Copa de la Liga Profesional | 2021/05/02 19:30 | Banfield v River Plate | L | 1-0 |
| Copa Libertadores | 2021/04/29 00:00 | River Plate v Junior | W | 2-1 |
| Argentina Copa de la Liga Profesional | 2021/04/25 21:00 | River Plate v San Lorenzo | L | 1-2 |
| Copa Libertadores | 2021/04/22 22:00 | Fluminense v River Plate | D | 1-1 |
Away History
| Copa Libertadores | 2021/05/13 00:00 | Fluminense v Independiente Santa Fe | L | 2-1 |
| Copa Libertadores | 2021/05/07 00:00 | Independiente Santa Fe v River Plate | D | 0-0 |
| Colombia Primera A | 2021/05/02 18:00 | Independiente Santa Fe v Junior | D | 0-0 |
| Copa Libertadores | 2021/04/29 00:00 | Independiente Santa Fe v Fluminense | L | 1-2 |
| Colombia Primera A | 2021/04/25 20:30 | Junior v Independiente Santa Fe | L | 3-1 |
| Copa Libertadores | 2021/04/23 02:00 | Junior v Independiente Santa Fe | D | 1-1 |
| Colombia Primera A | 2021/04/18 20:30 | La Equidad v Independiente Santa Fe | W | 1-2 |
| Colombia Primera A | 2021/04/12 01:00 | Independiente Santa Fe v Millonarios | L | 1-2 |