River Plate 2-1 Independiente Santa Fe 2021-05-20 00:00
Stadium: Estadio Monumental Antonio Vespucio Liberti Round: 5
Referee: Victor Hugo Carrillo Casanova Home Manager: Marcelo Gallardo Away Manager: Harold Rivera Roa
Head to Head
| Copa Libertadores | 2021/05/07 00:00 | Independiente Santa Fe v River Plate | D | 0-0 |
| Copa Libertadores | 2018/05/04 00:30 | Independiente Santa Fe v River Plate | W | 0-1 |
| Copa Libertadores | 2018/04/05 22:15 | River Plate v Independiente Santa Fe | D | 0-0 |
| Recopa Sudamericana | 2016/08/26 00:15 | River Plate v Independiente Santa Fe | W | 2-1 |