[9] Wolverhampton 3-1 Southampton [12] 2022-01-15 15:00
Stadium: Molineux Stadium Round: 22
Referee: Michael Salisbury Home Manager: Bruno Lage Away Manager: Ralph Hasenhuttl
Head to Head
| England Premier League | 2021/09/26 13:00 | Southampton v Wolverhampton | W | 0-1 |
| England Premier League | 2021/02/14 12:00 | Southampton v Wolverhampton | W | 1-2 |
| England FA Cup | 2021/02/11 17:30 | Wolverhampton v Southampton | L | 0-2 |
| England Premier League | 2020/11/23 20:00 | Wolverhampton v Southampton | D | 1-1 |
| England Premier League | 2020/01/18 15:00 | Southampton v Wolverhampton | W | 2-3 |
| England Premier League | 2019/10/19 14:00 | Wolverhampton v Southampton | D | 1-1 |
| England Premier League | 2019/04/13 14:00 | Southampton v Wolverhampton | L | 3-1 |
| England Premier League | 2018/09/29 14:00 | Wolverhampton v Southampton | W | 2-0 |
Home History
| England FA Cup | 2022/01/09 14:00 | Wolverhampton v Sheff Utd | W | 3-0 |
| England Premier League | 2022/01/03 17:30 | Man Utd v Wolverhampton | W | 0-1 |
| England Premier League | 2021/12/19 14:00 | Wolverhampton v Chelsea | D | 0-0 |
| England Premier League | 2021/12/15 19:30 | Brighton v Wolverhampton | W | 0-1 |
| England Premier League | 2021/12/11 12:30 | Man City v Wolverhampton | L | 1-0 |
| England Premier League | 2021/12/04 15:00 | Wolverhampton v Liverpool | L | 0-1 |
| England Premier League | 2021/12/01 19:30 | Wolverhampton v Burnley | D | 0-0 |
| England Premier League | 2021/11/27 15:00 | Norwich v Wolverhampton | D | 0-0 |
Away History
| England Premier League | 2022/01/11 19:45 | Southampton v Brentford | W | 4-1 |
| England FA Cup | 2022/01/08 17:30 | Swansea v Southampton | W | 2-3 |
| England Premier League | 2021/12/28 15:00 | Southampton v Tottenham | D | 1-1 |
| England Premier League | 2021/12/26 15:00 | West Ham v Southampton | W | 2-3 |
| England Premier League | 2021/12/15 19:30 | Crystal Palace v Southampton | D | 2-2 |
| England Premier League | 2021/12/11 15:00 | Arsenal v Southampton | L | 3-0 |
| England Premier League | 2021/12/04 15:00 | Southampton v Brighton | D | 1-1 |
| England Premier League | 2021/12/01 19:30 | Southampton v Leicester | D | 2-2 |