Stadium: Taffy Abel Arena Round: 1
| NCAAH | 2021/10/23 22:00 | Lake Superior State v Union (NY) | W | 5-2 |
| NCAAH | 2021/10/22 23:00 | Lake Superior State v Union (NY) | W | 7-4 |
| NCAAH | 2021/10/16 22:07 | Lake Superior State v St. Thomas (MN) | W | 6-3 |
| NCAAH | 2021/10/15 23:07 | Lake Superior State v St. Thomas (MN) | W | 3-1 |
| NCAAH | 2021/10/09 23:00 | Michigan v Lake Superior State | L | 7-4 |
| NCAAH | 2021/10/08 23:30 | Michigan v Lake Superior State | L | 6-1 |
| NCAAH | 2021/10/03 23:07 | Nebraska Omaha v Lake Superior State | L | 3-0 |
| NCAAH | 2021/10/03 00:07 | Nebraska Omaha v Lake Superior State | W | 3-4 |
| NCAAH | 2021/10/16 23:05 | Rochester Inst v St. Lawrence | L | 2-1 |
| NCAAH | 2021/10/10 00:07 | Colorado College v St. Lawrence | D | 1-1 |
| NCAAH | 2021/10/09 01:07 | Colorado College v St. Lawrence | W | 1-2 |
| NCAAH | 2021/03/20 20:00 | Quinnipiac v St. Lawrence | W | 2-3 |
| NCAAH | 2021/02/27 21:00 | St. Lawrence v Quinnipiac | L | 2-3 |
| NCAAH | 2021/02/26 21:00 | St. Lawrence v Quinnipiac | L | 2-4 |
| NCAAH | 2021/02/14 00:30 | Sacred Heart v St. Lawrence | D | 2-2 |
| NCAAH | 2021/02/06 21:00 | Quinnipiac v St. Lawrence | L | 2-1 |