Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2022/11/05 18:30 | NW Missouri State v Missouri Southern Lions | L | 27-5 |
| NCAAF | 2021/11/06 19:00 | Missouri Southern Lions v NW Missouri State | L | 7-49 |
| NCAAF | 2019/09/21 23:00 | Missouri Southern Lions v NW Missouri State | L | 34-66 |
| NCAAF | 2018/09/15 18:30 | NW Missouri State v Missouri Southern Lions | L | 63-0 |