| French Open Women | 05/25 14:05 | 14 | [108] Viktoriya Tomova v Natalia Vikhlyantseva [163] | 6-3,6-4 | |
| WTA Charleston | 04/12 20:30 | 25 | [82] Madison Brengle v Natalia Vikhlyantseva [149] | 6-0,3-6,6-2 | |
| WTA Charleston Qual | 04/10 15:00 | 14 | [151] Natalia Vikhlyantseva v Storm Sanders [187] | Cancelled | |
| WTA Charleston | 04/05 15:40 | 24 | [151] Natalia Vikhlyantseva v Zarina Diyas [88] | 3-6,1-6 | |
| WTA Charleston | 04/04 14:00 | 19 | [153] Natalia Vikhlyantseva v Alycia Parks [322] | 6-4,6-1 | |
| WTA Charleston | 04/03 14:00 | 14 | [153] Natalia Vikhlyantseva v Oksana Kalashnikova [64] | 6-0,6-0 | |
| WTA St. Petersburg | 03/13 11:10 | 14 | [148] Natalia Vikhlyantseva v Valeria Savinykh [226] | 6-2,4-6,1-6 | |
| WTA Dubai | 03/06 08:55 | 14 | [225] Aleksandra Krunic v Natalia Vikhlyantseva [148] | 6-2,6-3 | |
| Australian Open Women | 01/11 07:05 | 60 | [225] Valeria Savinykh v Natalia Vikhlyantseva [145] | 6-2,6-4 | |
| ITF W100 Dubai | 12/07 07:30 | 54 | [145] Natalia Vikhlyantseva v Elena Gabriela Ruse [177] | 2-6,4-6 | |
| ITF W100 Dubai | 12/06 11:55 | 54 | [145] Natalia Vikhlyantseva v Julia Wachaczyk [115] | 6-3,6-4 | |
| French Open Women | 09/22 14:00 | 14 | [136] Natalia Vikhlyantseva v Vera Zvonareva [182] | 1-6,2-6 | |
| US Open Women | 09/01 17:55 | 23 | Natalia Vikhlyantseva v Katrina Scott | 6-7,2-6 | |
| WTA Indian Wells | 03/03 18:00 | 25 | [125] Natalia Vikhlyantseva v Jessica Pegula [78] | 4-6,6-7 | |
| WTA Indian Wells | 03/02 18:00 | 24 | [125] Natalia Vikhlyantseva v Anhelina Kalinina [140] | 2-6,7-6,6-4 | |
| WTA Doha | 02/21 16:20 | 45 | [71] Daria Kasatkina v Natalia Vikhlyantseva [123] | Retired | |
| WTA Dubai | 02/15 06:30 | 44 | [122] Natalia Vikhlyantseva v Daria Kasatkina [71] | 3-6,2-6 | |
| WTA St. Petersburg | 02/09 11:00 | 64 | [89] Vitalia Diatchenko v Natalia Vikhlyantseva [120] | 7-6,6-4 | |
| WTA St. Petersburg | 02/08 13:00 | 45 | [208] Anastasiya Komardina v Natalia Vikhlyantseva [120] | 3-6,3-6 | |
| ITF W60 Andrezieux-Boutheon | 02/01 17:30 | 28 | [113] Natalia Vikhlyantseva v Arantxa Rus [93] | 4-6,5-7 | |
| ITF W60 Andrezieux-Boutheon | 01/31 17:00 | 27 | [113] Natalia Vikhlyantseva v Rebecca Sramkova [174] | 6-4,6-2 | |
| ITF W60 Andrezieux-Boutheon | 01/30 16:25 | 26 | [113] Natalia Vikhlyantseva v Audrey Albie [329] | 2-6,6-1,6-0 | |
| ITF W60 Andrezieux-Boutheon | 01/29 09:00 | 25 | Natalia Vikhlyantseva v Tessah Andrianjafitrimo | 6-3,6-3 | |
| Australian Open Women | 01/18 02:50 | 46 | [112] Natalia Vikhlyantseva v Kaja Juvan [126] | 3-6,3-6 | |
| Australian Open Women | 01/17 01:05 | 45 | [112] Natalia Vikhlyantseva v Isabella Shinikova [163] | 6-2,6-3 | |
| Australian Open Women | 01/16 01:20 | 44 | [112] Natalia Vikhlyantseva v Marta Kostyuk [149] | 7-5,6-2 | |
| WTA Brisbane | 01/05 03:25 | 46 | [41] Veronika Kudermetova v Natalia Vikhlyantseva [115] | 5-7,6-4,6-2 | |
| WTA Brisbane | 01/04 03:35 | 45 | [130] Maddison Inglis v Natalia Vikhlyantseva [115] | 6-4,3-6,5-7 | |
| WTA Limoges | 12/17 10:05 | 25 | [61] Anna Blinkova v Natalia Vikhlyantseva [114] | 6-3,7-5 | |
| ITF W80 Poitiers | 10/25 17:25 | 27 | [232] Oceane Dodin v Natalia Vikhlyantseva [100] | 7-6,6-2 |