| WTA Prague | 04/30 15:40 | 25 | [85] Kristyna Pliskova v Natalia Vikhlyantseva [113] | 3-6,4-6 | |
| WTA Charleston | 04/01 15:20 | 24 | [112] Natalia Vikhlyantseva v Tatjana Maria [59] | 2-6,5-7 | |
| WTA Miami | 03/20 19:10 | 23 | [104] Natalia Vikhlyantseva v Magdalena Rybarikova [74] | 6-1,5-7,6-7 | |
| WTA Indian Wells | 03/11 18:00 | 25 | [112] Natalia Vikhlyantseva v Angelique Kerber [8] | 6-3,1-6,3-6 | |
| WTA Indian Wells | 03/09 19:00 | 24 | [24] Carla Suarez Navarro v Natalia Vikhlyantseva [112] | 2-6,0-6 | |
| WTA Indian Wells | 03/07 21:20 | 23 | [112] Natalia Vikhlyantseva v Priscilla Hon [142] | 6-1,6-1 | |
| WTA Indian Wells | 03/05 19:00 | 45 | [81] Dalila Jakupovic v Natalia Vikhlyantseva [112] | 6-7,1-6 | |
| WTA Indian Wells | 03/04 19:00 | 44 | Zoe Kruger v Natalia Vikhlyantseva | 0-6,0-6 | |
| WTA Indian Wells | 02/27 01:45 | 25 | [18] Qiang Wang v Natalia Vikhlyantseva [112] | 2-6,6-0,6-3 | |
| WTA Indian Wells | 02/25 19:25 | 24 | [200] Lauren Davis v Natalia Vikhlyantseva [112] | 7-5,4-6,4-6 | |
| WTA Budapest | 02/19 13:15 | 25 | [105] Anna Blinkova v Natalia Vikhlyantseva [110] | 3-6,6-4,6-4 | |
| WTA Budapest | 02/18 13:35 | 64 | [110] Natalia Vikhlyantseva v Arina Rodionova [159] | 6-7,6-2,7-6 | |
| WTA Budapest | 02/17 13:55 | 45 | [109] Natalia Vikhlyantseva v Dalma Galfi [311] | 4-6,6-1,7-5 | |
| 2019 Fed Cup | 02/09 16:00 | 29 | [109] Natalia Vikhlyantseva v Johanna Larsson [71] | 7-6,6-2 | |
| 2019 Fed Cup | 02/07 15:00 | - | Natalia Vikhlyan'eva v Clara Tauson | 7-6,6-1 | |
| 2019 Fed Cup | 02/06 15:00 | 1 | [109] Natalia Vikhlyantseva v Iga Swiatek [141] | 6-0,6-2 | |
| WTA St. Petersburg | 01/28 10:15 | 54 | [109] Natalia Vikhlyantseva v Tereza Martincova [181] | 4-6,1-6 | |
| WTA St. Petersburg | 01/27 12:30 | 46 | [63] Andrea Petkovic v Natalia Vikhlyantseva [134] | 4-6,4-6 | |
| WTA St. Petersburg | 01/26 12:55 | 45 | Natalia Vikhlyantseva v Daria Mishina | 6-1,6-2 | |
| Australian Open Women | 01/17 02:50 | 24 | [145] Timea Bacsinszky v Natalia Vikhlyantseva [134] | 6-2,7-5 | |
| Australian Open Women | 01/15 03:35 | 23 | [134] Natalia Vikhlyantseva v Varvara Lepchenko [140] | 6-7,6-2,6-4 | |
| Australian Open Women | 01/11 02:20 | 46 | [174] Danka Kovinic v Natalia Vikhlyantseva [135] | 5-7,3-6 | |
| Australian Open Women | 01/10 05:05 | 45 | [159] Bibiane Schoofs v Natalia Vikhlyantseva [135] | 0-6,3-6 | |
| Australian Open Women | 01/09 00:30 | 44 | [153] Ying-Ying Duan v Natalia Vikhlyantseva [135] | 7-6,4-6,4-6 | |
| WTA Shenzhen | 12/29 04:20 | 64 | [135] Natalia Vikhlyantseva v Nao Hibino [113] | 2-6,2-6 | |
| ITF Women Dubai | 12/11 10:30 | 25 | [43] Kristina Mladenovic v Natalia Vikhlyantseva [134] | 6-3,6-3 | |
| WTA Limoges | 11/05 09:00 | 25 | [183] Jamie Loeb v Natalia Vikhlyantseva [134] | 6-2,6-4 | |
| ITF Women Poitiers | 10/28 13:30 | 29 | [107] Viktorija Golubic v Natalia Vikhlyantseva [152] | 3-6,6-1,7-5 | |
| ITF Women Poitiers | 10/27 12:30 | 28 | [152] Natalia Vikhlyantseva v Tereza Smitkova [133] | 6-3,7-6 | |
| ITF Women Poitiers | 10/26 18:25 | 27 | [152] Natalia Vikhlyantseva v Magdalena Frech [147] | 6-3,6-4 |