| WTA Madrid | 05/06 15:55 | 24 | Kristyna Pliskova v Natalia Vikhlyantseva | 6-4,6-4 | |
| WTA Madrid Qual | 05/05 12:35 | 46 | Magda Linette v Natalia Vikhlyantseva | 5-7,7-6,6-7 | |
| WTA Madrid Qual | 05/04 16:15 | 45 | Paula Badosa Gibert v Natalia Vikhlyantseva | 2-6,4-6 | |
| WTA Prague | 05/02 09:00 | 26 | Natalia Vikhlyantseva v Petra Kvitova | 3-6,1-6 | |
| WTA Prague | 04/30 11:25 | 25 | Natalia Vikhlyantseva v Carina Witthoeft | 6-4,6-4 | |
| WTA Charleston | 04/02 14:00 | 24 | Laura Siegemund v Natalia Vikhlyantseva | 7-5,6-2 | |
| WTA Miami | 03/23 21:00 | 24 | Venus Williams v Natalia Vikhlyantseva | 7-5,6-4 | |
| WTA Miami | 03/21 21:35 | 23 | Natalia Vikhlyantseva v Rebecca Peterson | 7-5,6-1 | |
| WTA Miami Qual | 03/20 14:00 | 45 | Natalia Vikhlyantseva v Nicole Gibbs | 7-6,6-4 | |
| WTA Miami Qual | 03/19 14:00 | 44 | Natalia Vikhlyantseva v Emiliana Arango | 6-3,6-2 | |
| WTA Indian Wells | 03/10 20:35 | 24 | Natalia Vikhlyantseva v Julia Goerges | 4-6,1-6 | |
| WTA Indian Wells | 03/08 20:45 | 23 | Vera Zvonareva v Natalia Vikhlyantseva | 3-6,2-6 | |
| WTA Indian Wells | 02/26 19:00 | 25 | Nicole Gibbs v Natalia Vikhlyantseva | 7-5,6-2 | |
| 2018 Fed Cup | 02/11 14:00 | 27 | Jana Cepelova v Natalia Vikhlyantseva | 6-4,6-4 | |
| 2018 Fed Cup | 02/10 14:30 | 27 | Viktoria Kuzmova v Natalia Vikhlyantseva | 4-6,2-6 | |
| WTA St. Petersburg Qual | 01/29 08:00 | 54 | Natalia Vikhlyantseva v Viktoria Kuzmova | 2-6,5-7 | |
| WTA St. Petersburg Qual | 01/28 10:20 | 46 | Natalia Vikhlyantseva v Jana Cepelova | 6-3,6-2 | |
| WTA St. Petersburg Qual | 01/27 11:40 | 45 | Natalia Vikhlyantseva v Valentyna Ivakhnenko | 6-2,6-1 | |
| Australian Open Women | 01/16 05:40 | 23 | Natalia Vikhlyantseva v Lesia Tsurenko | 6-3,3-6,4-6 | |
| WTA Hobart | 01/08 00:00 | 25 | Marketa Vondrousova v Natalia Vikhlyantseva | 6-4,6-3 | |
| WTA Brisbane Qual | 12/30 03:05 | 46 | Natalia Vikhlyantseva v Dayana Yastremska | Walkover | |
| WTA Brisbane Qual | 12/29 01:35 | 45 | Natalia Vikhlyantseva v Viktoriya Tomova | 7-6,6-3 | |
| WTA Moscow | 10/20 13:45 | 28 | Natalia Vikhlyantseva v Julia Goerges | 2-6,6-2,5-7 | |
| WTA Moscow | 10/19 15:30 | 27 | Alize Cornet v Natalia Vikhlyantseva | 6-4,5-7,3-6 | |
| WTA Moscow | 10/18 17:55 | 26 | Natalia Vikhlyantseva v Elena Vesnina | 7-6,6-4 | |
| WTA Moscow | 10/17 09:55 | 25 | Natalia Vikhlyantseva v Kaia Kanepi | 6-3,6-2 | |
| WTA Linz | 10/12 18:30 | 26 | Natalia Vikhlyantseva v Sorana Cirstea | 6-7,4-6 | |
| WTA Linz | 10/09 15:30 | 25 | Natalia Vikhlyantseva v Veronica Cepede Royg | 6-0,6-2 | |
| WTA Beijing | 09/30 10:45 | 24 | Natalia Vikhlyantseva v Daria Kasatkina | 6-7,1-6 | |
| WTA Beijing Qual | 09/29 04:15 | 45 | Natalia Vikhlyantseva v Aliaksandra Sasnovich | Cancelled |