| Challenger Genova | 09/05 18:30 | 25 | [218] Salvatore Caruso v Paolo Lorenzi [94] | 2-6,6-3,4-6 | |
| US Open | 08/29 20:40 | 24 | [66] Guido Pella v Paolo Lorenzi [94] | 7-5,6-0,6-2 | |
| US Open | 08/27 15:00 | 23 | [94] Paolo Lorenzi v Kyle Edmund [16] | 4-6,6-4,7-5,6-1 | |
| ATP Winston-Salem | 08/20 19:00 | 24 | Paolo Lorenzi v Marton Fucsovics | Cancelled | |
| Challenger Cordenons | 08/19 16:00 | 29 | [103] Paolo Lorenzi v Mate Valkusz [367] | 6-3,3-6,6-4 | |
| Challenger Cordenons | 08/18 17:00 | 28 | [103] Paolo Lorenzi v Joao Domingues [247] | 7-6,7-5 | |
| Challenger Cordenons | 08/17 17:00 | 27 | [103] Paolo Lorenzi v Tommy Robredo [207] | 6-3,6-3 | |
| Challenger Cordenons | 08/16 17:30 | 26 | [103] Paolo Lorenzi v Alessandro Bega [314] | 6-4,6-3 | |
| Challenger Cordenons | 08/15 16:00 | 25 | [103] Paolo Lorenzi v Steven Diez [320] | 7-5,7-6 | |
| Challenger Pullach | 08/07 09:00 | 25 | [339] Gianluca Mager v Paolo Lorenzi [97] | 6-4,3-6,6-2 | |
| Challenger Sopot | 08/05 13:00 | 29 | [183] Daniel Gimeno-Traver v Paolo Lorenzi [110] | 6-7,7-6,3-6 | |
| Challenger Sopot | 08/04 12:05 | 28 | [242] Zdenek Kolar v Paolo Lorenzi [110] | 4-6,0-6 | |
| Challenger Sopot | 08/03 12:45 | 27 | [174] Oscar Otte v Paolo Lorenzi [110] | 6-3,3-6,2-6 | |
| Challenger Sopot | 08/01 12:10 | 26 | [295] Jan Choinski v Paolo Lorenzi [110] | 5-7,0-6 | |
| Challenger Sopot | 07/31 10:25 | 25 | [359] Nicola Kuhn v Paolo Lorenzi [110] | 3-6,0-6 | |
| ATP Gstaad | 07/24 13:50 | 25 | Guido Pella v Paolo Lorenzi | Cancelled | |
| ATP Gstaad | 07/24 13:45 | 25 | [314] Oriol Roca Batalla v Paolo Lorenzi [109] | 6-3,6-7,6-3 | |
| ATP Umag | 07/17 15:00 | 25 | [88] Paolo Lorenzi v Evgeny Donskoy [83] | 3-6,4-6 | |
| Wimbledon | 07/04 12:10 | 24 | [86] Paolo Lorenzi v Gael Monfils [44] | 6-3,3-6,6-7,6-7 | |
| Wimbledon | 07/02 15:45 | 23 | [90] Laslo Djere v Paolo Lorenzi [86] | 6-7,7-6,2-6,4-6 | |
| ATP Antalya | 06/26 12:30 | 25 | [86] Paolo Lorenzi v Mirza Basic [78] | 3-6,3-6 | |
| Challenger L'Aquila | 06/24 12:45 | 29 | [190] Facundo Bagnis v Paolo Lorenzi [93] | 2-6,6-3,6-4 | |
| Challenger L'Aquila | 06/23 16:15 | 28 | [138] Thiago Monteiro v Paolo Lorenzi [93] | 6-7,7-6,3-6 | |
| Challenger L'Aquila | 06/22 15:35 | 27 | [317] Filippo Baldi v Paolo Lorenzi [93] | 4-6,6-7 | |
| Challenger L'Aquila | 06/21 15:00 | 26 | Riccardo Balzerani v Paolo Lorenzi | 4-6,4-6 | |
| Challenger L'Aquila | 06/19 17:45 | 25 | [267] Carlos Boluda-Purkiss v Paolo Lorenzi [93] | 5-7,6-3,4-6 | |
| Challenger Caltanissetta | 06/12 18:00 | 25 | [74] Paolo Lorenzi v Alejandro D-Fokina [393] | 4-6,0-6 | |
| French Open | 05/29 09:00 | 23 | [74] Paolo Lorenzi v Kevin Anderson [7] | 1-6,2-6,4-6 | |
| ATP Madrid | 05/08 13:40 | 24 | [37] Fernando Verdasco v Paolo Lorenzi [72] | 7-5,6-4 | |
| ATP Istanbul | 05/04 16:20 | 27 | [110] Laslo Djere v Paolo Lorenzi [76] | 6-7,7-5,7-6 |