| ATP New York | 02/11 19:55 | 25 | [76] Tennys Sandgren v Paolo Lorenzi [111] | 6-7,7-6,4-6 | |
| ATP Cordoba | 02/04 22:10 | 25 | [114] Paolo Lorenzi v Guido Pella [59] | 1-6,3-6 | |
| ATP Cordoba | 02/03 20:25 | 164 | [114] Paolo Lorenzi v Alessandro Giannessi [167] | 7-6,4-6,6-7 | |
| ATP Cordoba | 02/02 22:05 | 64 | [114] Paolo Lorenzi v Facundo Arguello [193] | 3-6,6-3,6-4 | |
| Challenger Newport Beach | 01/22 19:40 | 25 | [116] Paolo Lorenzi v Filip Peliwo [240] | 4-6,6-3,4-6 | |
| Australian Open | 01/11 00:50 | 46 | [109] Paolo Lorenzi v Daniel Evans [190] | 3-6,3-6 | |
| Australian Open | 01/10 02:25 | 45 | [109] Paolo Lorenzi v Tommy Paul [195] | 7-6,4-6,6-3 | |
| Australian Open | 01/08 23:00 | 44 | [109] Paolo Lorenzi v Daniel Elahi Galan [222] | 6-4,6-2 | |
| ATP Doha | 12/31 12:30 | 25 | [28] Fernando Verdasco v Paolo Lorenzi [109] | 6-3,6-4 | |
| ATP Doha | 12/30 12:30 | 164 | [110] Paolo Lorenzi v Ricardas Berankis [117] | 4-6,6-7 | |
| ATP Doha | 12/29 08:00 | 64 | Paolo Lorenzi v Jabor Al Mutawa | 6-1,6-0 | |
| Challenger Andria | 11/22 18:00 | 26 | [304] Roberto Marcora v Paolo Lorenzi [109] | 6-3,7-6 | |
| Challenger Andria | 11/21 19:00 | 25 | [452] Andrea Pellegrino v Paolo Lorenzi [109] | 4-6,2-6 | |
| Challenger Houston | 11/14 18:10 | 26 | [115] Paolo Lorenzi v Thai-Son Kwiatkowski [310] | 4-6,4-6 | |
| Challenger Houston | 11/13 17:35 | 25 | [115] Paolo Lorenzi v Stefan Kozlov [414] | 6-4,3-6,6-4 | |
| Challenger Montevideo | 11/08 17:00 | 26 | [127] Carlos Berlocq v Paolo Lorenzi [115] | 3-6,6-2,7-5 | |
| Challenger Montevideo | 11/06 15:00 | 25 | [322] Federico Coria v Paolo Lorenzi [115] | 6-3,0-6,6-7 | |
| Challenger Guayaquil | 10/31 18:00 | 26 | [116] Paolo Lorenzi v Pedja Krstin [195] | 6-7,2-6 | |
| Challenger Guayaquil | 10/30 20:35 | 25 | [116] Paolo Lorenzi v Martin Cuevas [286] | 6-4,6-7,7-6 | |
| Challenger Lima | 10/24 19:20 | 26 | [269] Facundo Arguello v Paolo Lorenzi [114] | 6-4,7-6 | |
| Challenger Lima | 10/23 17:30 | 25 | [160] Gerald Melzer v Paolo Lorenzi [114] | 6-7,6-7 | |
| Challenger Santo Domingo | 10/11 22:00 | 27 | [115] Paolo Lorenzi v Federico Delbonis [81] | 5-7,5-7 | |
| Challenger Santo Domingo | 10/11 15:55 | 26 | [115] Paolo Lorenzi v Gerald Melzer [146] | 7-6,7-6 | |
| Challenger Santo Domingo | 10/10 01:40 | 25 | [115] Paolo Lorenzi v Juan P Varillas [339] | 3-6,6-1,6-0 | |
| Challenger Monterrey | 10/03 01:25 | 25 | [113] Paolo Lorenzi v Jurgen Melzer [155] | 5-7,3-6 | |
| Challenger Biella | 09/21 10:50 | 27 | [114] Paolo Lorenzi v Stefano Travaglia [150] | 2-6,5-7 | |
| Challenger Biella | 09/20 09:30 | 26 | [114] Paolo Lorenzi v Ricardo Ojeda Lara [297] | 6-2,6-1 | |
| Challenger Biella | 09/18 10:00 | 25 | [114] Paolo Lorenzi v Mathias Bourgue [321] | 6-2,6-4 | |
| Challenger Szczecin | 09/10 11:15 | 25 | [113] Paolo Lorenzi v Sergio Gutierrez-Ferrol [160] | 4-6,6-3,5-7 | |
| Challenger Genova | 09/06 13:30 | 26 | [198] Lukas Rosol v Paolo Lorenzi [94] | 7-6,6-3 |