| International Tennis Series | 04/20 12:00 | 1 | Paolo Lorenzi v Adrian Andreev | 4-2,3-4,2-4 | |
| International Tennis Series | 04/19 17:00 | 1 | [121] Paolo Lorenzi v Jamie Cerretani [150] | 4-1,4-1 | |
| International Tennis Series | 04/19 16:00 | 1 | [121] Paolo Lorenzi v Evan King [407] | 2-4,4-1,4-2 | |
| International Tennis Series | 04/19 14:00 | 1 | Preston Brown v Paolo Lorenzi | 3-4,0-4 | |
| International Tennis Series | 04/18 18:00 | 1 | Paolo Lorenzi v Adrian Andreev | 4-3,4-2 | |
| International Tennis Series | 04/18 16:00 | 1 | [121] Paolo Lorenzi v Evan King [407] | 4-0,4-2 | |
| International Tennis Series | 04/18 13:00 | 1 | Emmett Ward v Paolo Lorenzi | 1-4,2-4 | |
| Challenger Monterrey | 03/05 18:30 | 26 | [269] Ulises Blanch v Paolo Lorenzi [122] | 6-4,5-7,6-4 | |
| Challenger Monterrey | 03/04 18:00 | 25 | [274] James Ward v Paolo Lorenzi [122] | 3-6,7-6,3-6 | |
| ATP Santiago | 02/25 23:30 | 25 | [121] Paolo Lorenzi v Alejandro Tabilo [166] | 3-6,4-6 | |
| ATP Delray Beach | 02/15 16:30 | 64 | [116] Paolo Lorenzi v Noah Rubin [269] | 5-7,6-7 | |
| ATP New York | 02/12 17:00 | 26 | [54] Miomir Kecmanovic v Paolo Lorenzi [116] | 6-3,6-3 | |
| ATP New York | 02/11 19:30 | 25 | [116] Paolo Lorenzi v Danilo Petrovic [159] | 4-6,6-4,6-0 | |
| ATP New York | 02/10 17:00 | 164 | [116] Paolo Lorenzi v Noah Rubin [269] | 6-3,6-1 | |
| ATP New York | 02/09 18:30 | 64 | [115] Paolo Lorenzi v Guillermo Garcia-Lopez [165] | 7-5,6-3 | |
| ATP Pune | 02/04 10:00 | 25 | [115] Paolo Lorenzi v Egor Gerasimov [90] | 2-6,3-6 | |
| Challenger Bangkok 2 | 01/21 10:10 | 25 | [116] Paolo Lorenzi v Sasikumar Mukund [267] | 3-6,2-6 | |
| Australian Open | 01/16 05:00 | 45 | [114] Paolo Lorenzi v Lukas Rosol [177] | 7-6,6-7,5-7 | |
| Australian Open | 01/14 00:00 | 44 | [114] Paolo Lorenzi v Adrian Menendez-Maceiras [219] | 6-3,6-3 | |
| Challenger Maia | 11/22 18:00 | 27 | [120] Paolo Lorenzi v Jozef Kovalik [172] | 5-7,5-7 | |
| Challenger Maia | 11/21 17:05 | 26 | [120] Paolo Lorenzi v Filippo Baldi [212] | 1-6,7-6,6-3 | |
| Challenger Maia | 11/20 15:00 | 25 | [120] Paolo Lorenzi v Jurij Rodionov [308] | 3-6,7-6,7-6 | |
| Challenger Knoxville | 11/05 19:40 | 25 | [189] Dmitry Popko v Paolo Lorenzi [118] | 4-6,6-2,6-4 | |
| Challenger Guayaquil | 10/31 21:05 | 26 | [117] Paolo Lorenzi v Francisco Cerundolo [251] | 3-6,6-7 | |
| Challenger Guayaquil | 10/31 00:40 | 25 | [117] Paolo Lorenzi v Martin Cuevas [440] | 7-5,6-4 | |
| Challenger Brest | 10/23 08:00 | 25 | [120] Paolo Lorenzi v Zdenek Kolar [268] | 3-6,6-7 | |
| ATP Antwerp | 10/14 11:45 | 164 | Gregoire Barrere v Paolo Lorenzi | 6-1,6-4 | |
| ATP Antwerp | 10/13 16:00 | 64 | Arnaud Bovy v Paolo Lorenzi | 7-6,1-6,4-6 | |
| Challenger Mouilleron le Captif | 10/10 09:00 | 26 | [90] Marius Copil v Paolo Lorenzi [118] | 2-6,7-6,6-2 | |
| Challenger Mouilleron le Captif | 10/09 09:50 | 25 | [416] Rayane Roumane v Paolo Lorenzi [118] | 6-7,2-6 |