| WTA Madrid | 04/30 12:15 | 24 | [48] Magda Linette v Saisai Zheng [57] | 2-6,6-3,1-6 | |
| WTA Istanbul | 04/20 08:00 | 25 | Kristina Mladenovic v Saisai Zheng | Cancelled | |
| WTA Bogota | 04/07 18:55 | 26 | [49] Saisai Zheng v Stefanie Voegele [127] | 4-6,1-6 | |
| WTA Bogota | 04/05 15:00 | 25 | [49] Saisai Zheng v Usue Maitane Arconada [157] | 6-3,6-1 | |
| WTA Miami | 03/26 16:20 | 24 | [6] Karolina Pliskova v Saisai Zheng [53] | 6-2,6-1 | |
| WTA Miami | 03/24 17:15 | 23 | [53] Saisai Zheng v Fiona Ferro [44] | 2-6,6-4,6-3 | |
| WTA Monterrey | 03/19 19:00 | 27 | [72] Ann Li v Saisai Zheng [52] | 7-5,6-1 | |
| WTA Monterrey | 03/18 19:00 | 26 | [101] Lin Zhu v Saisai Zheng [52] | 1-6,2-6 | |
| WTA Monterrey | 03/16 20:00 | 25 | [94] Varvara Gracheva v Saisai Zheng [52] | 3-6,5-7 | |
| WTA Dubai | 03/08 08:00 | 24 | [48] Saisai Zheng v Elena Rybakina [23] | 0-6,4-6 | |
| WTA Doha | 03/02 16:25 | 25 | [48] Saisai Zheng v Misaki Doi [83] | 4-6,3-6 | |
| WTA Doha | 03/02 11:00 | - | Saisai Zheng v Amanda Anisimova | View | |
| WTA Adelaide | 02/22 08:00 | 25 | [47] Saisai Zheng v Danielle Collins [37] | 6-7,1-6 | |
| WTA Melbourne | 02/14 02:35 | 24 | [245] Francesca Jones v Saisai Zheng [44] | 6-2,3-6,6-2 | |
| Australian Open Women | 02/09 05:25 | 23 | [44] Saisai Zheng v Barbora Krejcikova [59] | 3-6,6-2,2-6 | |
| WTA Gippsland Trophy | 01/31 08:00 | 24 | [79] Irina-Camelia Begu v Saisai Zheng [42] | 3-6,7-5,6-4 | |
| 2020 Fed Cup | 03/07 12:00 | 5 | [34] Saisai Zheng v Su Jeong Jang [309] | 6-1,6-0 | |
| 2020 Fed Cup | 03/06 11:50 | 4 | Saisai Zheng v Yasmina Karimjanova | 6-0,6-1 | |
| 2020 Fed Cup | 03/05 12:00 | 3 | Saisai Zheng v Ya-Yi Yang | 6-1,6-2 | |
| Billie Jean King Cup | 03/04 12:00 | 2 | Saisai Zheng v Janice Tjen | 6-1,6-1 | |
| WTA Doha | 02/27 12:30 | 27 | [37] Saisai Zheng v Aryna Sabalenka [13] | 6-3,6-7,3-6 | |
| WTA Doha | 02/26 13:15 | 26 | [6] Kiki Bertens v Saisai Zheng [37] | 6-3,3-6,4-6 | |
| WTA Doha | 02/25 12:30 | 25 | [424] Vera Zvonareva v Saisai Zheng [37] | 5-7,1-6 | |
| WTA Doha | 02/24 12:30 | 24 | [37] Saisai Zheng v Marketa Vondrousova [18] | 1-6,6-3,6-2 | |
| WTA Dubai | 02/15 13:35 | 44 | [36] Saisai Zheng v Katerina Siniakova [59] | 6-7,4-6 | |
| WTA Hua Hin | 02/14 07:00 | 27 | [105] Patricia Maria Tig v Saisai Zheng [36] | 6-4,6-2 | |
| WTA Hua Hin | 02/12 08:00 | 26 | [238] En Shuo Liang v Saisai Zheng [36] | 4-6,3-6 | |
| WTA Hua Hin | 02/10 08:00 | 25 | [183] Natalija Kostic v Saisai Zheng [36] | 6-7,0-6 | |
| Australian Open Women | 01/22 00:00 | 24 | [4] Naomi Osaka v Saisai Zheng [42] | 6-2,6-4 | |
| Australian Open Women | 01/20 00:00 | 23 | [42] Saisai Zheng v Anna Kalinskaya [109] | 6-3,6-2 |